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    Biomarkers and Electrocardiographic Evidence of Myocardial Ischemia in Patients With Human Immunodeficiency Virus Infection

    American Journal of Cardiology
    Vol. 111Issue 5p760–764Published online: January 7, 2013
    • Mihir Gupta
    • Christopher J. Miller
    • Jason V. Baker
    • Jason Lazar
    • Johannes R. Bogner
    • Alexandra Calmy
    • and others
    Cited in Scopus: 8
      We assessed the relation of inflammatory and coagulation biomarkers with electrocardiographic (ECG) evidence of myocardial ischemia. High-sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6), and D-dimer levels were measured at study entry for 3,085 human immunodeficiency virus-infected participants (mean age 44 years; 26.4% women; 24.6% black) in the Strategies for Management of Antiretroviral Therapy trial. Logistic regression models were used to examine the associations of these biomarkers with prevalent and incident myocardial ischemia.
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