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- Valvular heart disease
Frequency and Causes of Stroke During or After Transcatheter Aortic Valve Implantation
American Journal of CardiologyVol. 109Issue 11p1637–1643Published online: March 19, 2012- Rutger-Jan Nuis
- Nicolas M. Van Mieghem
- Carl J. Schultz
- Adriaan Moelker
- Robert M. van der Boon
- Robert Jan van Geuns
- and others
Cited in Scopus: 131Transcatheter aortic valve implantation (TAVI) is invariably associated with the risk of clinically manifest transient or irreversible neurologic impairment. We sought to investigate the incidence and causes of clinically manifest stroke during TAVI. A total of 214 consecutive patients underwent TAVI with the Medtronic-CoreValve System from November 2005 to September 2011 at our institution. Stroke was defined according to the Valve Academic Research Consortium recommendations. Its cause was established by analyzing the point of onset of symptoms, correlating the symptoms with the computed tomography-detected defects in the brain, and analyzing the presence of potential coexisting causes of stroke, in addition to a multivariate analysis to determine the independent predictors.
