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Insulin-mediated glucose uptake in congestive heart failure

      Paolisso et al
      • Paolisso G.
      • Tagliamonte M.R.
      • Rizzo M.R.
      • Gambardella A.
      • Gualdiero P.
      • Lama D.
      • Varricchio G.
      • Gentile S.
      • Varricchio M.
      Prognostic importance of insulin-mediated glucose uptake in aged patients with congestive heart failure secondary to mitral and/or aortic valve disease.
      recently reported on impaired insulin-mediated glucose metabolism in 174 patients with congestive heart failure (CHF) and its relation to neurohormones, tumor necrosis factor-α (TNF-α), and prognosis. This is by far the largest study of insulin resistance in CHF to date. However, we have some concerns that limit the application of the results.
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