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Avoiding revascularization with lifestyle changes: the multicenter lifestyle demonstration project

  • Dean Ornish
    Correspondence
    Address for reprints: Dean Ornish, MD, University of California-San Francisco School of Medicine; Preventive Medicine Research Institute, 900 Bridgeway, Suite 1, Sausalito, California 94965
    Affiliations
    Preventive Medicine Research Institute, Sausalito, California, USA
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  • for the Multicenter Lifestyle Demonstration Project Research Group

      Abstract

      The Multicenter Lifestyle Demonstration Project was designed to determine if comprehensive lifestyle changes can be a direct alternative to revascularization for selected patients without increasing cardiac events. A total of 333 patients completed this demonstration project (194 in the experimental group and 139 in the control group). We found that experimental group patients were able to avoid revascularization for at least 3 years by making comprehensive lifestyle changes at substantially lower cost without increasing cardiac morbidity and mortality. These patients reported reductions in angina comparable with what can be achieved with revascularization.
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