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Serum lipid profiles and the presence of yellow plaque in coronary lesions in vivo

  • Katsuhiro Kitamura
    Affiliations
    From the First Department of Internal Medicine, National Defense Medical College, Chiba, Japan

    From the Department of Internal Medicine, Chiba Hokusoh Hospital, Nippon Medical School, Kamakari, Inba, Chiba, Japan
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  • Author Footnotes
    1 Dr. Mizuno's address is: Department of Internal Medicine, Chiba Hokusoh Hospital, Nippon Medical School, 1715, Kamakari, Inba, Chiba, 270-16, Japan.
    Kyoichi Mizuno
    Footnotes
    1 Dr. Mizuno's address is: Department of Internal Medicine, Chiba Hokusoh Hospital, Nippon Medical School, 1715, Kamakari, Inba, Chiba, 270-16, Japan.
    Affiliations
    From the First Department of Internal Medicine, National Defense Medical College, Chiba, Japan

    From the Department of Internal Medicine, Chiba Hokusoh Hospital, Nippon Medical School, Kamakari, Inba, Chiba, Japan
    Search for articles by this author
  • Akira Miyamoto
    Affiliations
    From the First Department of Internal Medicine, National Defense Medical College, Chiba, Japan

    From the Department of Internal Medicine, Chiba Hokusoh Hospital, Nippon Medical School, Kamakari, Inba, Chiba, Japan
    Search for articles by this author
  • Haruo Nakamura
    Affiliations
    From the First Department of Internal Medicine, National Defense Medical College, Chiba, Japan

    From the Department of Internal Medicine, Chiba Hokusoh Hospital, Nippon Medical School, Kamakari, Inba, Chiba, Japan
    Search for articles by this author
  • Author Footnotes
    1 Dr. Mizuno's address is: Department of Internal Medicine, Chiba Hokusoh Hospital, Nippon Medical School, 1715, Kamakari, Inba, Chiba, 270-16, Japan.
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      Abstract

      In conclusion, this is the first report showing that the serum lipid profile is related to plaque composition in vivo. Yellow plaque detected by coronary angioscopy may be lipid-rich and vulnerable to disruption, so more intensive follow-up and therapy may be needed.
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      References

        • Mizuno K
        • Satomura K
        • Miyamoto A
        • Arakawa K
        • Shibuya T
        • Arai T
        • Kurita A
        • Nakamura H
        • Ambrose JA
        Angioscopic evaluation of coronary-artery thrombi in acute coronary syndromes.
        N Engl J Med. 1992; 326: 287-290
        • Mizuno K
        • Miyamoto A
        • Satomura K
        • Kurita A
        • Arai T
        • Sakurada M
        • Yanagida S
        • Nakamura H
        Angioscopic coronary macromorphology in patients with acute coronary disorders.
        Lancet. 1991; 1: 809-812
        • Ramee SR
        • White CJ
        • Collins TJ
        • Mesa JE
        • Murgo JP
        Percutaneous angioscopy during coronary angioplasty using a steerable microangioscope.
        J Am Coll Cardiol. 1991; 17: 100-105
        • de Feyter PJ
        • Ozaki Y
        • Baptista J
        • Escaned J
        • Di Mario C
        • de Jaegere PPT
        • Serruys PW
        • Roelandt JRTC
        Ischemia-related lesion characteristics in patients with stable or unstable angina. A study with intracoronary angioscopy and ultrasound.
        Circulation. 1995; 92: 1408-1413
        • Lindop G
        Blood vessels and lymphatics.
        in: 12th ed. Muir's Text-book of Pathology. Edward Arnold, London1985: 3-14
        • Smith EB
        The relationship between plasma and tissue lipids in human atherosclerosis.
        Adv Lipid Res. 1974; 12: 1-49
        • Kannel WB
        • Castelli WP
        • Gordon T
        • McNamara P
        Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham Study.
        Ann Intern Med. 1971; 74: 1-12
        • Neaton JD
        • Kuller LH
        • Wentworth D
        • Borhani NO
        Total and cardiovascular mortality in relation to cigarette smoking, serum cholesterol concentration, and diastolic blood pressure among black and white males followed up for five years (MRFIT).
        Am Heart J. 1984; 108: 759-769
        • Stender S
        • Zilversmit DB
        Transfer of plasma lipoprotein components and of plasma proteins into aortas of cholesterol-fed rabbits: molecular size as a determinant of plasma lipoprotein influx.
        Arteriosclerosis. 1981; 1: 28-49
        • Faggiotto A
        • Ross R
        • Harker L
        Studies of hypercholesterolemia in the non-human primate.
        Arteriosclerosis. 1984; 4: 323-356
        • Srinivasan SR
        • Dolan P
        • Radhakrishnamurthy B
        • Pargaonkar PS
        • Berenson GS
        Lipoprotein-acid mucopolysaccharide complexes of human atherosclerotic lesions.
        Biochim Biophys Acta. 1975; 388: 58-70
        • Hollander W
        Unified concept on the role of acid mucopolysaccharides and connective tissue proteins in the accumulation of lipids, lipoproteins, and calcium in the atherosclerotic plaque.
        Exp Mol Pathol. 1976; 25: 106-120
        • Sanbandam T
        • Baker JR
        • Christner JE
        • Ekborg SL
        Specificity of low density lipoprotein-glycosaminoglycan interaction.
        Arterioscler Thromb. 1991; 11: 561-568
        • Blankenhorn DH
        The infiltration of carotenoids into human atheromas and xanthomas.
        Ann Intern Med. 1960; 53: 944-954
        • Blankenhorn DH
        • Freiman DG
        • Knowles HC
        Carotenoids in man: the distribution of epiphasic carotenoids in atherosclerotic lesions.
        J Clin Invest. 1956; 35: 1243-1247
        • Watts GF
        • Lewis B
        • Brunt JNH
        • Lewis ES
        • Coltart DJ
        • Smith LDR
        • Mann JI
        • Swan AV
        Effects on coronary artery disease of lipid-lowering diet, or diet plus cholestyramine, in the St. Thomas' Atherosclerosis Regression Study (STARS).
        Lancet. 1992; 339: 563-569
        • Buchwald H
        • Varco RL
        • Matts JP
        • Long JM
        • Fitch LL
        • Campbell GS
        Effect of partial ileal bypass on mortality and morbidity from coronary heart disease in patients with hypercholesterolemia: report of the Program on Surgical Control of the Hyperlipidemias (POSCH).
        N Engl J Med. 1990; 323: 946-955
        • Brown BG
        • Albers JJ
        • Fisher LD
        • Schaefer SM
        • Lin JT
        • Kaplan CK
        • Zhao XQ
        • Bisson BD
        • Fitzpatrick VF
        • Dodge HT
        Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B.
        N Engl J Med. 1990; 323: 1289-1298
        • Falk E
        Why do plaques rapture?.
        Circulation. 1992; 86: III-30-III-42
        • Davies MJ
        • Thomas AC
        Plaque fissuring: the cause of acute myocardial infarction, sudden ischemic death, and crescendo angina.
        Br Heart J. 1985; 53: 363-373