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Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California

Incidence of myocardial infarction and death from coronary heart disease
  • Thomas L. Robertson
    Correspondence
    Address for reprints: Thomas L, Robertson, MD, Environmental Protection Agency, University of North Carolina, Medical Research Building C-224H, Chapel Hill, North Carolina 27514.
    Affiliations
    From the Departments of Medicine, Radiation Effects Research Foundation (formerly Atomic Bomb Casualty Commission), Hiroshima and Nagasaki, Japan

    U. S. Public Health Service, assigned to the Radiation Effects Research Foundation by the Health Effects Research Laboratory, U. S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA
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  • Hiroo Kato
    Affiliations
    Epidemiology and Statistics, Radiation Effects Research Foundation (formerly Atomic Bomb Casualty Commission), Hiroshima and Nagasaki, Japan
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  • George G. Rhoads
    Affiliations
    the Honolulu Heart Study, U. S. National Heart, Lung, and Blood Institute, Honolulu, Hawaii and Bethesda, Maryland, USA

    School of Public Health, University of Hawaii, Honolulu, Hawaii, USA
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  • Abraham Kagan
    Affiliations
    the Honolulu Heart Study, U. S. National Heart, Lung, and Blood Institute, Honolulu, Hawaii and Bethesda, Maryland, USA
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  • Michael Marmot
    Affiliations
    the School of Public Health, University of California at Berkeley, Berkeley, California, USA
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  • S. Leonard Syme
    Affiliations
    the School of Public Health, University of California at Berkeley, Berkeley, California, USA
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  • Tavia Gordon
    Affiliations
    Biometrics Research Branch, U. S. National Heart, Lung, and Blood Institute, Bethesda, Maryland, USA
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  • Robert M. Worth
    Affiliations
    School of Public Health, University of Hawaii, Honolulu, Hawaii, USA
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  • Author Footnotes
    †† Present address: Department of Medicine, Danbury Hospital, Danbury, Connecticut.
    Joseph L. Belsky
    Footnotes
    †† Present address: Department of Medicine, Danbury Hospital, Danbury, Connecticut.
    Affiliations
    From the Departments of Medicine, Radiation Effects Research Foundation (formerly Atomic Bomb Casualty Commission), Hiroshima and Nagasaki, Japan
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  • Author Footnotes
    ‡‡ Present address: Department of Medicine, Hospital of St. Raphael, 1450 Chapel St., New Haven, Connecticut.
    Donald S. Dock
    Footnotes
    ‡‡ Present address: Department of Medicine, Hospital of St. Raphael, 1450 Chapel St., New Haven, Connecticut.
    Affiliations
    From the Departments of Medicine, Radiation Effects Research Foundation (formerly Atomic Bomb Casualty Commission), Hiroshima and Nagasaki, Japan
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  • Michihiro Miyanishi
    Affiliations
    Department of Internal Medicine, School of Medicine, Hiroshima University, Hiroshima, Japan
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  • Sadahisa Kawamoto M.D.
    Affiliations
    From the Departments of Medicine, Radiation Effects Research Foundation (formerly Atomic Bomb Casualty Commission), Hiroshima and Nagasaki, Japan
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  • Author Footnotes
    †† Present address: Department of Medicine, Danbury Hospital, Danbury, Connecticut.
    ‡‡ Present address: Department of Medicine, Hospital of St. Raphael, 1450 Chapel St., New Haven, Connecticut.
      This paper is only available as a PDF. To read, Please Download here.
      The incidence of myocardial infarction and death from coronary heart disease was studied in defined samples of 45 to 68 year old Japanese men in Japan, Hawaii and California. The incidence rate was lowest in Japan where it was half that observed in Hawaii (P < 0.01). The youngest men in the sample in Japan were at particularly low risk. The incidence among Japanese men in California was nearly 50 percent greater than that of Japanese in Hawaii (P < 0.05). A striking increase in the incidence of myocardial infarction appears to have occurred in the Japanese who migrated to the United States; this increase is more pronounced in California than in Hawaii.
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