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Effect of Anticoagulation Duration on Stroke Incidence in Asian Patients With Left Ventricular Thrombus

Published:January 24, 2023DOI:https://doi.org/10.1016/j.amjcard.2022.12.022
      Left ventricular thrombus (LVT) occurs in acute myocardial infarction (AMI) and in ischemic and nonischemic cardiomyopathies.
      • Lattuca B
      • Bouziri N
      • Kerneis M
      • Portal JJ
      • Zhou J
      • Hauguel-Moreau M
      • Mameri A
      • Zeitouni M
      • Guedeney P
      • Hammoudi N
      • Isnard R
      • Pousset F
      • Collet JP
      • Vicaut E
      • Montalescot G
      • Silvain J
      ACTION Study Group
      Antithrombotic therapy for patients with left ventricular mural thrombus.
      ,
      • Lemaître AI
      • Picard F
      • Maurin V
      • Faure M
      • Dos Santos P
      • Girerd N
      Clinical profile and midterm prognosis of left ventricular thrombus in heart failure.
      LVT may result in embolic stroke.
      • Leow AS
      • Sia CH
      • Tan BY
      • Kaur R
      • Yeo TC
      • Chan MY
      • Tay EL
      • Seet RC
      • Loh JP
      • Yeo LL
      Characterisation of acute ischemic stroke in patients with left ventricular thrombi after myocardial infarction.
      We read with interest the study by Lorente-Ros et al
      • Lorente-Ros Á
      • Alonso-Salinas GL
      • Monteagudo Ruiz JM
      • Abellás-Sequeiros M
      • Vieítez-Florez JM
      • Sánchez Vega D
      • Álvarez-Garcia J
      • Sanmartín-Fernández M
      • Lorente-Ros M
      • Del Prado Díaz S
      • Fernández Golfín C
      • Zamorano Gómez JL
      Effect of duration of anticoagulation in the incidence of stroke in patients with left-ventricular thrombus.
      published in the American Journal of Cardiology. That study, conducted in a Spanish cohort, found that prolonged anticoagulation >12 months for LVT was associated with lower stroke risk. We aimed to study the generalizability of these results in an Asian population because the original article was a single-center study with limited representation.
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