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Meta-Analysis of Coronary Computed Tomography Versus Invasive Coronary Angiography in Stable Chest Pain

Published:September 17, 2022DOI:https://doi.org/10.1016/j.amjcard.2022.08.014
      Coronary artery disease (CAD) is the most prevalent cardiovascular disease and is the foremost cause of mortality worldwide.
      • Khan MA
      • Hashim MJ
      • Mustafa H
      • Baniyas MY
      • Al Suwaidi SKBM
      • AlKatheeri R
      • Alblooshi FMK
      • Almatrooshi MEAH
      • Alzaabi MEH
      • Al Darmaki RS
      • Lootah SNAH
      Global epidemiology of ischemic heart disease: results from the Global Burden of Disease study.
      Coronary computed tomography angiography (CCTA) is a noninvasive alternative tool for the diagnosis of obstructive CAD. This tool has been evaluated in randomized controlled trials (RCTs) in patients with stable chest pain and intermediate probability of CAD.
      • Haase R
      • Schlattmann P
      • Gueret P
      • Andreini D
      • Pontone G
      • Alkadhi H
      • Hausleiter J
      • Garcia MJ
      • Leschka S
      • Meijboom WB
      • Zimmermann E
      • Gerber B
      • Schoepf UJ
      • Shabestari AA
      • Nørgaard BL
      • Meijs MFL
      • Sato A
      • Ovrehus KA
      • Diederichsen ACP
      • Jenkins SMM
      • Knuuti J
      • Hamdan A
      • Halvorsen BA
      • Mendoza-Rodriguez V
      • Rochitte CE
      • Rixe J
      • Wan YL
      • Langer C
      • Bettencourt N
      • Martuscelli E
      • Ghostine S
      • Buechel RR
      • Nikolaou K
      • Mickley H
      • Yang L
      • Zhang Z
      • Chen MY
      • Halon DA
      • Rief M
      • Sun K
      • Hirt-Moch B
      • Niinuma H
      • Marcus RP
      • Muraglia S
      • Jakamy R
      • Chow BJ
      • Kaufmann PA
      • Tardif JC
      • Nomura C
      • Kofoed KF
      • Laissy JP
      • Arbab-Zadeh A
      • Kitagawa K
      • Laham R
      • Jinzaki M
      • Hoe J
      • Rybicki FJ
      • Scholte A
      • Paul N
      • Tan SY
      • Yoshioka K
      • Röhle R
      • Schuetz GM
      • Schueler S
      • Coenen MH
      • Wieske V
      • Achenbach S
      • Budoff MJ
      • Laule M
      • Newby DE
      • Dewey M
      COME-CCT Consortium
      Diagnosis of obstructive coronary artery disease using computed tomography angiography in patients with stable chest pain depending on clinical probability and in clinically important subgroups: meta-analysis of individual patient data.
      However, there is uncertainty regarding its usefulness compared with invasive coronary angiography (ICA) in reducing cardiovascular outcomes in this patient population.
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