Introduction
- Page 2nd, RL
- Allen LA
- Kloner RA
- Carriker CR
- Martel C
- Morris AA
- Piano MR
- Rana JS
- Saucedo JF
Medical marijuana, recreational cannabis, and cardiovascular health: a scientific statement From the American Heart Association.
Methods
Results
Variable | Never (n=1345) | Current (n=40) | Past (n=71) | Use, recency unknown (n=29) |
---|---|---|---|---|
Age, mean (±SD) | 74 ±8 | 67 ±5 | 67 ±4 | 69 ±6 |
Male | 47% | 70% | 77% | 62% |
Alcohol use | 42% | 80% | 49% | 62% |
Cigarette smoking | ||||
Never | 50% | 15% | 14% | 10% |
Former | 45% | 65% | 73% | 76% |
Current | 5% | 20% | 13% | 14% |
Height (cm), mean (±SD) | 165 ±9 | 174 ±10 | 173 ±10 | 171 ±8 |
Weight (lb), mean (±SD) | 170 ±38 | 183 ±37 | 189 ±38 | 185 ±25 |
Diabetes mellitus | 24% | 10% | 17% | 17% |
Systolic blood pressure (mmHg), mean (±SD) | 128 ±20 | 125 ±20 | 128 ±19 | 130 ±20 |
Hypertension | 65% | 53% | 54% | 69% |
Education | ||||
High school | 13% | 3% | 7% | 14% |
Some college | 45% | 53% | 51% | 52% |
Finished college | 43% | 45% | 42% | 34% |
Prior myocardial infarction, stroke or heart failure | 7% | 3% | 7% | 3% |
Unadjusted | Minimally adjusted | Fully adjusted † Adjustment for age, sex, race/ethnicity, height, weight, diabetes, systolic blood pressure, hypertension, cigarette smoking (never, former, current), alcohol use and education. CI = confidence interval; SVT = supraventricular tachycardia; NSVT = non-sustained ventricular tachycardia; PAC = premature atrial contraction; PVC = premature ventricular contraction. | ||||
---|---|---|---|---|---|---|
Geometric mean ratio | 95% CI | Geometric mean ratio | 95% CI | Geometric mean ratio | 95% CI | |
Atrial arrhythmias | ||||||
Runs of SVT/day | ||||||
Current use | 1.15 | (0.71, 1.86) | 1.56 | (0.94,2.59) | 1.42 | (0.87, 2.32) |
Past use | 0.65 | (0.46, 0.92) | 0.91 | (0.64, 1.30) | 0.87 | (0.61, 1.24) |
PACs/hour | ||||||
Current use | 0.80 | (0.44, 1.47) | 1.17 | (0.67, 2.07) | 1.22 | (0.72, 2.13) |
Past use | 0.78 | (0.45, 1.35) | 1.12 | (0.66, 1.90) | 1.14 | (0.67, 1.94) |
Ventricular arrhythmias | ||||||
Runs of NSVT/day | ||||||
Current use | 1.42 | (1.04 1.93) | 1.29 | (0.95, 1.76) | 1.28 | (0.95, 1.73) |
Past use | 1.05 | (0.87, 1.28) | 0.94 | (0.77, 1.14) | 0.95 | (0.77, 1.16) |
PVCs/hour | ||||||
Current use | 1.34 | (0.52, 3.40) | 1.06 | (0.44, 2.51) | 1.02 | (0.55, 2.02) |
Past use | 1.67 | (0.92, 3.03) | 1.36 | (0.75, 2.45) | 1.24 | (0.64, 2.33) |
Unadjusted | Minimally adjusted | Fully adjusted † Adjustment for age, sex, race/ethnicity, height, weight, diabetes, systolic blood pressure, hypertension, cigarette smoking (never, former, current), alcohol use and education. CI = confidence interval; SVT = supraventricular tachycardia; NSVT = non-sustained ventricular tachycardia; PAC = premature atrial contraction; PVC = premature ventricular contraction. | ||||
---|---|---|---|---|---|---|
Geometric mean ratio | 95% CI | Geometric mean ratio | 95% CI | Geometric mean ratio | 95% CI | |
Atrial arrhythmias | ||||||
Runs of SVT/day | 1.33 | (0.69, 2.54) | 1.27 | (0.72, 2.28) | 1.33 | (0.82, 1.92) |
PACs/hour | 1.29 | (0.53, 3.15) | 1.07 | (0.45, 2.55) | 0.99 | (0.42, 2.34) |
Ventricular arrhythmias | ||||||
Runs of NSVT/day | 1.29 | (0.92, 1.82) | 1.39 | (0.99, 1.95) | 1.56 | (1.13, 2.17) |
PVCs/hour | 1.01 | (0.33, 3.09) | 0.99 | (0.36, 2.72) | 1.16 | (0.42, 3.19) |
Discussion
- Page 2nd, RL
- Allen LA
- Kloner RA
- Carriker CR
- Martel C
- Morris AA
- Piano MR
- Rana JS
- Saucedo JF
Medical marijuana, recreational cannabis, and cardiovascular health: a scientific statement From the American Heart Association.
Disclosures
Acknowledgment
Appendix. Supplementary materials
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This Multiethnic Study of Atherosclerosis research was supported by contracts 75N92020D00001 , HHSN268201500003I , N01-HC-95159 , 75N92020D00005 , N01-HC-95160 , 75N92020D00002 , N01-HC-95161 , 75N92020D00003 , N01-HC-95162 , 75N92020D00006 , N01-HC-95163 , 75N92020D00004 , N01-HC-95164 , 75N92020D00007 , N01-HC-95165 , N01-HC-95166 , N01-HC-95167 , N01-HC-95168 , and N01-HC-95169 and grant R01HL127659 from the National Heart, Lung, and Blood Institute, Bethesda, Maryland and by grants UL1-TR-000040 , UL1-TR-001079 , and UL1-TR-001420 from the National Center for Advancing Translational Sciences, Bethesda, Maryland . BNH received support from a National Heart, Lung and Blood Institute grant T32HL007828 .
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