Viral pneumonia represents a major cause of morbidity and mortality, especially among
older patients.
1
Viral pneumonia may be associated with a systemic inflammatory response, which has
been linked with arterial and venous thrombotic cardiovascular events.
2
During the recent COVID-19 pandemic due to the novel SARS-CoV-2 virus, anecdotal
and published experience suggests high rates of thrombotic complications among hospitalized
patients.
3
Due to a paucity of studies describing the incidence, predictors, and outcomes of
thrombotic events among patients with viral pneumonia, the observation of thrombosis
in patients with COVID-19 lacks context. Hence, we aimed to address this knowledge
gap using a large nationally representative dataset.- Bikdeli B
- Madhavan MV
- Jimenez D
- Chuich T
- Dreyfus I
- Driggin E
- Nigoghossian C
- Ageno W
- Madjid M
- Guo Y
- Tang LV
- Hu Y
- Giri J
- Cushman M
- Quéré I
- Dimakakos EP
- Gibson CM
- Lippi G
- Favaloro EJ
- Fareed J
- Caprini JA
- Tafur AJ
- Burton JR
- Francese DP
- Wang EY
- Falanga A
- McLintock C
- Hunt BJ
- Spyropoulos AC
- Barnes GD
- Eikelboom JW
- Weinberg I
- Schulman S
- Carrier M
- Piazza G
- Beckman JA
- Steg PG
- Stone GW
- Rosenkranz S
- Goldhaber SZ
- Parikh SA
- Monreal M
- Krumholz HM
- Konstantinides SV
- Weitz JI
- Lip GYH.
COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic
therapy, and follow-up: JACC State-of-the-Art Review.
J Am Coll Cardiol. 2020; 75: 2950-2973
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References
- Mortality associated with influenza and respiratory syncytial virus in the United States.JAMA. 2003; 289: 179-186
- Risk of myocardial infarction and stroke after acute infection or vaccination.N Engl J Med. 2004; 351: 2611-2618
- COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up: JACC State-of-the-Art Review.J Am Coll Cardiol. 2020; 75: 2950-2973
- Influence of influenza infection on in-hospital acute myocardial infarction outcomes.Am J Cardiol. 2020; 130: 7-14
Article info
Publication history
Published online: January 13, 2021
Received in revised form:
December 30,
2020
Received:
December 23,
2020
Identification
Copyright
© 2021 Elsevier Inc. All rights reserved.