Advertisement

Sleep Duration and Cardiovascular Health in a Representative Community Population (from NHANES, 2005 to 2016)

      The 2016 American Heart Association Scientific Statement on sleep duration and cardiovascular risk suggested that optimal sleep duration is critical for cardiovascular health, with both long and short sleep duration associated with adverse health outcomes. We examined the relation between sleep duration and cardiovascular health among the general population in the United States from 2005 to 2016. We sought to investigate associations between sleep duration and the prevalence of coronary artery disease, heart failure (HF), stroke, hypertension, diabetes mellitus (DM), and hyperlipidemia. Using the National Health and Nutrition Examination Survey, we identified all patients with HF, coronary artery disease, hypertension, hyperlipidemia, DM, and stroke from 2005 to 2016. Multivariable logistic regression analyses were performed to adjust for age, sex, body mass index (BMI), marital status, educational level, physical activity, sedentary activity, depression, blood pressure, lipid profiles, and hemoglobin. In total, 32,152 National Health and Nutrition Examination Survey participants responded to the sleep survey. Both short sleepers (<7 hours, n = 12,027) and long sleepers (>9 hours, n = 1,058) were older and more likely to have a higher BMI than optimal sleepers (7 to 9 hours, n = 19,067; all p values <0.05). After adjusting for confounding variables and in comparison to those with optimal sleep duration, short sleep duration was associated with a higher prevalence of previous stroke (odds ratio [OR] 1.45; 95% confidence intervals [CI] 1.23 to 1.70), HF (OR 1.65; 95% CI 1.40 to 1.95), DM (OR 1.35; 95% CI 1.23 to 1.49), and hyperlipidemia (OR 1.12; 95% CI 1.04 to 1.22), whereas long sleep duration was associated with a higher prevalence of previous stroke (OR 1.81; 95% CI 1.37 to 2.34) and HF (OR 1.47; 95% CI 1.08 to 1.97). In conclusion, both long and short sleep durations were associated with poor cardiovascular health in this cross-sectional study.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to American Journal of Cardiology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Watson NF
        • Badr MS
        • Belenky G
        • Bliwise DL
        • Buxton OM
        • Buysse D
        • Dinges DF
        • Gangwisch J
        • Grandner MA
        • Kushida C
        • Malhotra RK
        • Martin JL
        • Patel SR
        • Quan SF
        • Tasali E
        Recommended amount of sleep for a healthy adult: a joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society.
        Sleep. 2015; 38: 843-844
        • Liu Y
        Prevalence of healthy sleep duration among adults—United States, 2014.
        MMWR Mor Mortal Weekly Rep. 2016; 65: 137-141
        • Daghlas I
        • Dashti HS
        • Lane J
        • Aragam KG
        • Rutter MK
        • Saxena R
        • Vetter C
        Sleep duration and myocardial infarction.
        J Am Coll Cardiol. 2019; 74: 1304-1314
        • Gottlieb DJ
        • Redline S
        • Nieto FJ
        • Baldwin CM
        • Newman AB
        • Resnick HE
        • Punjabi NM
        Association of usual sleep duration with hypertension: the Sleep Heart Health Study.
        Sleep. 2006; 29: 1009-1014
        • Fang J
        • Wheaton AG
        • Keenan NL
        • Greenlund KJ
        • Perry GS
        • Croft JB
        Association of sleep duration and hypertension among US adults varies by age and sex.
        Am J Hypertens. 2012; 25: 335-341
        • Domínguez F
        • Fuster V
        • Fernández-Alvira JM
        • Fernández-Friera L
        • López-Melgar B
        • Blanco-Rojo R
        • Fernández-Ortiz A
        • García-Pavía P
        • Sanz J
        • Mendiguren JM
        • Ibañez B
        • Bueno H
        • Lara-Pezzi E
        • Ordovás JM
        Association of sleep duration and quality with subclinical atherosclerosis.
        J Am Coll Cardiol. 2019; 73: 134-144
        • Cappuccio FP
        • Cooper D
        • D'Elia L
        • Strazzullo P
        • Miller MA
        Sleep duration predicts cardiovascular outcomes: a systematic review and meta-analysis of prospective studies.
        Eur Heart J. 2011; 32: 1484-1492
        • Krittanawong C
        • Tunhasiriwet A
        • Wang Z
        • Zhang H
        • Farrell AM
        • Chirapongsathorn S
        • Sun T
        • Kitai T
        • Argulian E
        Association between short and long sleep durations and cardiovascular outcomes: a systematic review and meta-analysis.
        Eur Heart J Acute Cardiovasc Care. 2019; 8: 762-770
        • St-Onge MP
        • Grandner MA
        • Brown D
        • Conroy MB
        • Jean-Louis G
        • Coons M
        • Bhatt DL
        • American Heart Association Obesity, Behavior Change, Diabetes, and Nutrition Committees of the Council on Lifestyle and Cardiometabolic Health; Council on Cardiovascular Disease in the Young; Council on Clinical Cardiology; and Stroke Council
        Sleep duration and quality: impact on lifestyle behaviors and cardiometabolic health: a scientific statement from the American Heart Association.
        Circulation. 2016; 134: e367-e386
        • Anothaisintawee T
        • Reutrakul S
        • Van Cauter E
        • Thakkinstian A
        Sleep disturbances compared to traditional risk factors for diabetes development: systematic review and meta-analysis.
        Sleep Med Rev. 2016; 30: 11-24
        • Shan Z
        • Ma H
        • Xie M
        • Yan P
        • Guo Y
        • Bao W
        • Rong Y
        • Jackson CL
        • Hu FB
        • Liu L
        Sleep duration and risk of type 2 diabetes: a meta-analysis of prospective studies.
        Diabetes Care. 2015; 38: 529-537
        • Altman NG
        • Izci-Balserak B
        • Schopfer E
        • Jackson N
        • Rattanaumpawan P
        • Gehrman PR
        • Patel NP
        • Grandner MA
        Sleep duration versus sleep insufficiency as predictors of cardiometabolic health outcomes.
        Sleep Med. 2012; 13: 1261-1270
        • Zizi F
        • Pandey A
        • Murrray-Bachmann R
        • Vincent M
        • McFarlane S
        • Ogedegbe G
        • Jean-Louis G
        Race/ethnicity, sleep duration, and diabetes mellitus: analysis of the National Health Interview Survey.
        Am J Med. 2012; 125: 162-167
        • Chen JC
        • Brunner RL
        • Ren H
        • Wassertheil-Smoller S
        • Larson JC
        • Levine DW
        • Allison M
        • Naughton MJ
        • Stefanick ML
        Sleep duration and risk of ischemic stroke in postmenopausal women.
        Stroke. 2008; 39: 3185-3192
        • Fang J
        • Wheaton AG
        • Ayala C
        Sleep duration and history of stroke among adults from the USA.
        J Sleep Res. 2014; 23: 531-537
        • Spiegel K
        • Leproult R
        • L'Hermite-Baleriaux M
        • Copinschi G
        • Penev PD
        • Van Cauter E
        Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin.
        J Clin Endocrinol Metab. 2004; 89: 5762-5771
        • Spiegel K
        • Tasali E
        • Penev P
        • Van Cauter E
        Brief communication: sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite.
        Ann Intern Med. 2004; 141: 846-850
        • Patel SR
        • Zhu X
        • Storfer-Isser A
        • Mehra R
        • Jenny NS
        • Tracy R
        • Redline S
        Sleep duration and biomarkers of inflammation.
        Sleep. 2009; 32: 200-204
        • Greer SM
        • Goldstein AN
        • Walker MP
        The impact of sleep deprivation on food desire in the human brain.
        Nat Commun. 2013; 4: 2259
        • Rechtschaffen A
        • Bergmann BM.
        Sleep deprivation in the rat by the disk-over-water method.
        Behav Brain Res. 1995; 69: 55-63
        • Arora T
        • Jiang CQ
        • Thomas GN
        • Lam KB
        • Zhang WS
        • Cheng KK
        • Lam TH
        • Taheri S
        Self-reported long total sleep duration is associated with metabolic syndrome: the Guangzhou Biobank Cohort Study.
        Diabetes Care. 2011; 34: 2317-2319
        • Petrov ME
        • Howard G
        • Grandner MA
        • Kleindorfer D
        • Molano JR
        • Howard VJ
        Sleep duration and risk of incident stroke by age, sex, and race: the REGARDS study.
        Neurology. 2018; 91: e1702-e1709
        • Zonoozi S
        • Ramsay SE
        • Papacosta O
        • Lennon L
        • Ellins EA
        • Halcox JPJ
        • Whincup PH
        • Goya Wannamethee S
        Self-reported sleep duration and napping, cardiac risk factors and markers of subclinical vascular disease: cross-sectional study in older men.
        BMJ Open. 2017; 7e016396
        • Sharma B
        • Owens R
        • Malhotra A
        Sleep in congestive heart failure.
        Med Clin North Am. 2010; 94: 447-464
        • Meng L
        • Zheng Y
        • Hui R
        The relationship of sleep duration and insomnia to risk of hypertension incidence: a meta-analysis of prospective cohort studies.
        Hypertens Res. 2013; 36: 985-995
        • Guo X
        • Zheng L
        • Wang J
        • Zhang X
        • Zhang X
        • Li J
        • Sun Y
        Epidemiological evidence for the link between sleep duration and high blood pressure: a systematic review and meta-analysis.
        Sleep Med. 2013; 14: 324-332
        • Bin YS
        • Marshall NS
        • Glozier N
        Sleeping at the limits: the changing prevalence of short and long sleep durations in 10 countries.
        Am J Epidemiol. 2013; 177: 826-833
        • Gangwisch JE.
        Epidemiological evidence for the links between sleep, circadian rhythms and metabolism.
        Obes Rev. 2009; 10: 37-45
        • Gottlieb DJ
        • Punjabi NM
        • Mehra R
        • Patel SR
        • Quan SF
        • Babineau DC
        • Tracy RP
        • Rueschman M
        • Blumenthal RS
        • Lewis EF
        • Bhatt DL
        • Redline S
        CPAP versus oxygen in obstructive sleep apnea.
        N Engl J Med. 2014; 370: 2276-2285
        • Cespedes EM
        • Hu FB
        • Redline S
        • Rosner B
        • Alcantara C
        • Cai J
        • Hall MH
        • Loredo JS
        • Mossavar-Rahmani Y
        • Ramos AR
        • Reid KJ
        • Shah NA
        • Sotres-Alvarez D
        • Zee PC
        • Wang R
        • Patel SR
        Comparison of self-reported sleep duration with actigraphy: results from the Hispanic Community Health Study/Study of Latinos Sueno Ancillary Study.
        Am J Epidemiol. 2016; 183: 561-573