Energy drinks (EDs) are widely consumed by adolescents and young adults. Almost all
kinds of arrhythmias have been reported following EDs consumption, most of which is
atrial fibrillation (AF). Atrial conduction time prolongation and heterogeneous sinusal
impulses propagation to the atriums are the key electrophysiological mechanisms leading
AF. We aimed to evaluate the acute effects of Red Bull ED ingestion on atrial electromechanical
conduction times in healthy young adults. After a 12-hour fasting, 54 healthy young
adults consumed 330 mL of Red Bull ED. Atrial electromechanical coupling (PA), intra-atrial
electromechanical delay (intra-AEMD), and interatrial electromechanical delay (inter-AEMD)
were measured at baseline and 2-hour after Red Bull ED ingestion by echocardiographic
tissue-Doppler imaging (TDI) method. PA-lateral (49.7 ± 11.2 vs 54.1 ± 11.0 msn, p = 0.001)
and PA-septal (40.8 ± 9.1 vs 43.7 ± 10.5 msn, p = 0.032) times were statistically
significantly prolonged after Red Bull ED ingestion. There was also a statistically
significant increase in the duration of inter-AEMD (14.4 ± 10.6 vs 18.1 ± 8.5 msn,
p = 0.010) after ED ingestion. It was showed that even a single can of ED can acutely
increase atrial electromechanical conduction times in young adults. These findings
may be the cause of ED-associated AF.
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References
- A survey of energy drink consumption patterns among college students.Nutr J. 2007; 6: 35
Red Bull company figures. https://energydrink.redbull.com/company. Accessed April 5, 2019.
- Energy Drinks Could be Deadly for Young People with Heart Conditions, study Finds.ABC (16 February 2017), Sydney2017 (Accessed 30 Dec 2018)
- Energy beverages: content and safety.Mayo Clin Proc. 2010; 85: 1033-1041
- Review of published cases of adverse cardiovascular events after ingestion of energy drinks.Am J Cardiol. 2014; 113: 168-172
- Atrial fibrillation due to over the counter stimulant drugs in a young adult.J Clin Diagn Res. 2015; 8: 5-7
- Atrial fibrillation in healthy adolescents after highly caffeinated beverage consumption: two case reports.J Med Case Rep. 2011; 5: 18
- Energy drink consumption and cardiac complications: a case for caution.J Addict Med. 2016; 10: 280-282
- Energy drinks and atrial fibrillation in young adults.Clin Nutr. 2018; 37: 1073-1074
- Atrial fibrillation after ingestion of a high energy drink.An Pediatr. 2012; 77: 417-419
- Tissue velocity Doppler assessment of atrial and ventricular electromechanical coupling and atrioventricular time intervals in normal subjects.Am J Cardiol. 2003; 92: 1347-1350
- Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology.J Am Soc Echocardiogr. 2005; 18: 1440-1463
- Doppler tissue analysis of atrialel ectromechanical coupling in paroxysmal atrial fibrillation.J Am Soc Echocardiogr. 2005; 18: 39-44
- Health effects of energy drinks on children, adolescents, and young adults.Pediatrics. 2011; 127: 511-528
- Caffeine-induced cardiac arrhythmia: an unrecognized danger of health food products.Med J Aust. 2001; 174: 520-521
- Effects of caffeine on plasma renin activity, catecholamines and blood pressure.N Engl J Med. 1978; 298: 181-186
- Caffeinated energy drinks–a growing problem.Drug Alcohol Depend. 2009; 99: 1-10
- Cardiac actions of taurine as a modulator of the ion channels.Adv Exp Med Biol. 1998; 442: 121-128
- Effect of taurine on the refractory period of heart muscle.Physiologist. 1966; 9: 273
- Further evidence of localized posterior interatrial conduction delay in lone paroxysmal atrial fibrillation.Europace. 2001; 3: 100-107
- Intra- and interatrial conduction delay: implications for cardiac pacing.Pacing Clin Electrophysiol. 2004; 27: 507-525
- Assessment of atrial electromechanical coupling and influential factors in nonrheumatic paroxysmal atrial fibrillation.Clin Cardiol. 2008; 31: 74-78
- Activation of inward rectifier potassium channels accelerates atrial fibrillation in humans: evidence for a reentrant mechanism.Circulation. 2006; 114: 2434-2442
- Interatrial block and atrial arrhythmias in centenarians: prevalence, associations, and clinical implications.Heart Rhythm. 2016; 13: 645-651
- Interatrial conduction block and retrograde activation of the left atrium and paroxysmal supraventricular tachyarrhythmia.Eur Heart J. 1988; 9: 1112-1118
- Intra- and interatrial conduction abnormalities: hemodynamic and arrhythmic significance.J Interv Card Electrophysiol. 2018; 52: 293-302
Article Info
Publication History
Published online: November 19, 2019
Received in revised form:
November 11,
2019
Received:
October 8,
2019
Identification
Copyright
© 2019 Elsevier Inc. All rights reserved.
