Low work participation is well known in patients with chronic disease but has not
been described in patients with atrial septal defect (ASD). In this nation-wide cohort
study, we report the first long-term follow-up of use of permanent social security
benefits and work participation in adults with ASD. All Danes born before 1994 and
diagnosed with ASD from 1959 to 2013 (n = 2,277) were identified from the Danish medical
registries. We used Cox proportional hazards regression to compare the risk of receiving
permanent social security benefits in the ASD patients compared with an age- and gender-matched
general population cohort. Using the DREAM database, we calculated work participation
score and proportion of patients working or not working at the age of 30 years. Median
follow-up from ASD diagnosis was 23.4 years (range 0.2 to 59.3). ASD patients had
a higher risk of receiving permanent social security benefits (hazard ratio 2.3 [95%
confidence interval 2.1 to 2.6]) compared with the comparison cohort with 24% of the
ASD patients receiving permanent social security benefits at the end of follow-up
compared with 12% of the comparison cohort. At the age of 30 years, the proportion
not working was 28% in the ASD cohort and 18% in the comparison cohort. In patients
with ASD, 23% of those without a job had a psychiatric diagnosis. In conclusion, the
risk of receiving permanent social security benefits was twice as high in patients
with ASD and the work participation score was reduced compared with the background
population.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to American Journal of CardiologyAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Atrial septal defect closure in adulthood is associated with normal survival in the mid to longer term.Heart. 2019; 105: 1014-1019
- Excellent survival and low incidence of arrhythmias, stroke and heart failure long-term after surgical asd closure at young age. A prospective follow-up study of 21-33 years.Eur Heart J. 2003; 24: 190-197
- The unnatural history of an atrial septal defect: longitudinal 35 year follow-up after surgical closure at young age.Heart. 2013; 99: 1346-1352
- Long-term mortality in patients with atrial septal defect: a nationwide cohort-study.Eur Heart J. 2018; 39: 993-998
- Atrial fibrillation and stroke in adult patients with atrial septal defect and the long-term effect of closure.Heart. 2015; 101: 706-711
- Long-term risk of atrial fibrillation and stroke in patients with atrial septal defect diagnosed in childhood.Am J Cardiol. 2017; 119: 461-465
- Risk of pneumonia in adults with closed versus unclosed atrial septal defect (from a nationwide cohort study).Am J Cardiol. 2014; 114: 105-110
- Lifelong burden of small unrepaired atrial septal defect: results from the Danish National Patient registry.Int J Cardiol. 2019; 283: 101-106
- Small unrepaired atrial septal defects display impaired exercise capacity compared with healthy peers.Congenit Heart Dis. 2019; 14: 372-379
- Employment and advice regarding careers for adults with congenital heart disease.Cardiol Young. 2005; 15: 391-395
- Employment in adults with congenital heart disease.Arch Pediat Adolesc Med. 2002; 156: 1143-1148
- Common prognostic factors of work disability among employees with a chronic somatic disease: a systematic review of cohort studies.Scan J Work Environ Health. 2009; 35: 261-281
- The burden of migraine in adult with atrial septal defect: a nationwide cohort study.Sci Rep. 2019; 9: 7410
- The Danish Civil Registration system as a tool in epidemiology.Eur J Epidiomiol. 2014; 29: 541-549
- The Danish National Patient Register.Scan J Public Health. 2011; 39: 30-33
- Long-term nationwide follow-up study of simple congenital heart disease diagnosed in otherwise healthy children.Circulation. 2016; 133: 474-483
- Register-based follow-up of social benefits and other transfer payments: accuracy and degree of completeness in a Danish interdepartmental administrative database compared with a population-based survey.Scan J Public Health. 2007; 35: 497-502
- Disability pensions in relation to stroke: a population study.Brain Inj. 2002; 16: 997-1009
- Identification of major depressive disorder among the long-term unemployed.Soc Psychiatry Psychiatr Epidemiol. 2018; 53: 45-52
- Long-term socioeconomic consequences and health care costs of childhood and adolescent-onset epilepsy.Epilepsia. 2016; 57: 1078-1085
- The socioeconomic consequences of multiple sclerosis: a controlled national study.Eur Neuropsychopharmacol. 2012; 22: 36-43
- Prevalence of Norwegian patients diagnosed with childhood cancer, their working ability and need of health insurance benefits.Acta Oncol. 2007; 46: 60-66
- Prevalence of psychopathology in children of parents with mental illness and/or addiction: an up to date narrative review.Curr Opin Psychiatry. 2017; 30: 312-317
Article info
Publication history
Published online: September 09, 2019
Received in revised form:
August 21,
2019
Received:
June 25,
2019
Footnotes
Funding: The Augustinus Foundation, Copenhagen, Denmark
Karen Elise Jensens Foundation, Copenhagen, Denmark
Central Denmark Region, Viborg, Denmark.
Role of funding: None of the funders had any role in; study design, or collection, analysis, and interpretation of data, or writing the manuscript or decision to submit.
Identification
Copyright
© 2019 Elsevier Inc. All rights reserved.
