Advertisement

Outcomes With Intravascular Ultrasound-Guided Drug Eluting Stent Implantation for Unprotected Left Main Coronary Lesions: A Meta-analysis

      Randomized controlled trials (RCTs) have demonstrated that intravascular (IVUS) guidance improves outcomes after drug-eluting stent (DES) implantation.
      • Elgendy IY
      • Mahmoud AN
      • Elgendy AY
      • Bavry AA
      Outcomes With Intravascular Ultrasound-Guided Stent Implantation: A Meta-Analysis of Randomized Trials in the Era of Drug-Eluting Stents.
      • Elgendy IY
      • Mahmoud AN
      • Elgendy AY
      • Mintz GS
      Intravascular ultrasound-guidance is associated with lower cardiovascular mortality and myocardial infarction for drug-eluting stent implantation Insights from an updated meta-analysis of randomized trials.
      However, left main coronary artery (LMCA) lesions were excluded or under-represented in these trials. With the projected increase in the rates of LMCA percutaneous coronary intervention (PCI) procedures after the publication of recent DES versus bypass surgery trials,
      • Valle JA
      • Tamez H
      • Abbott JD
      • Moussa ID
      • Messenger JC
      • Waldo SW
      • Kennedy KF
      • Masoudi FA
      • Yeh RW
      Contemporary use and trends in unprotected left main coronary artery percutaneous coronary intervention in the United States: an analysis of the National Cardiovascular Data Registry research to practice initiative.
      we sought to perform a meta-analysis examining the effect of IVUS-guidance on individual outcomes after DES implantation for LMCA lesions.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to American Journal of Cardiology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Elgendy IY
        • Mahmoud AN
        • Elgendy AY
        • Bavry AA
        Outcomes With Intravascular Ultrasound-Guided Stent Implantation: A Meta-Analysis of Randomized Trials in the Era of Drug-Eluting Stents.
        Circ Cardiovasc Interv. 2016; 9: e003700https://doi.org/10.1161/CIRCINTERVENTIONS
        • Elgendy IY
        • Mahmoud AN
        • Elgendy AY
        • Mintz GS
        Intravascular ultrasound-guidance is associated with lower cardiovascular mortality and myocardial infarction for drug-eluting stent implantation Insights from an updated meta-analysis of randomized trials.
        Circ J. 2019; 83: 1410-1413
        • Valle JA
        • Tamez H
        • Abbott JD
        • Moussa ID
        • Messenger JC
        • Waldo SW
        • Kennedy KF
        • Masoudi FA
        • Yeh RW
        Contemporary use and trends in unprotected left main coronary artery percutaneous coronary intervention in the United States: an analysis of the National Cardiovascular Data Registry research to practice initiative.
        JAMA Cardiol. 2019; 4: 100-109
        • Mahmoud AN
        • Gad MM
        • Elgendy AY
        • Elgendy IY
        • Bavry AA
        Efficacy and safety of aspirin for primary prevention of cardiovascular events: a meta-analysis and trial sequential analysis of randomized controlled trials.
        Eur Heart J. 2019; 40: 607-617
        • Choi KH
        • Song YB
        • Lee JM
        • Lee SY
        • Park TK
        • Yang JH
        • Choi JH
        • Choi SH
        • Gwon HC
        • Hahn JY
        Impact of intravascular ultrasound-guided percutaneous coronary intervention on long-term clinical outcomes in patients undergoing complex procedures.
        JACC Cardiovasc Interv. 2019; 12: 607-620
        • Mintz GS
        • Lefèvre T
        • Lassen JF
        • Testa L
        • Pan M
        • Singh J
        • Stankovic G
        • Banning AP
        Intravascular ultrasound in the evaluation and treatment of left main coronary artery disease: a consensus statement from the European Bifurcation Club.
        EuroIntervention. 2018; 14: e467-e474