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Extracorporeal Membrane Oxygenation (ECMO): A Promising Option for Treating Adult Down Syndrome Patients?

      Down syndrome (DS) remains the most common chromosomal disorder with the incidence of 1 in 700 babies in the United States. DS increases the risk of respiratory and congenital heart defects and therefore, increasing the need for extra life support.
      • Benhaourech S
      • Drighil A
      Congenital heart disease and Down syndrome: various aspects of a confirmed association.
      Without surgery, congenital heart disease is a major source of morbidity and premature death. The life expectancy of patients with DS without any congenital heart defects is 60 to 70 years of age. However, patients with congenital heart defects have 5 times higher risk of death as compared with people without any congenital defects.
      • Layangool T
      • Sangtawesin C
      Survival analysis of Down syndrome with congenital heart disease: a 5-years registry at QSNICH.
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      References

        • Benhaourech S
        • Drighil A
        Congenital heart disease and Down syndrome: various aspects of a confirmed association.
        Cardiovasc J Afr. 2016; 27: 287-290
      1. http://www.nads.org/resources/facts-about-down-syndrome/

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        Survival analysis of Down syndrome with congenital heart disease: a 5-years registry at QSNICH.
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        Extracorporeal membrane oxygenation characteristics and outcomes in adult patients with Down syndrome.
        Artif Organs. 2018; 42: 921-925
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        Extracorporeal membrane oxygenation in severe acute respiratory failure. A randomized prospective study.
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