Advertisement

Abnormal P-Wave Axis and Risk of Atrial Fibrillation: Not Just the Left Atrial Enlargement but Other Factors Also Play a Significant Role

      Maheshwari et al. reported a commendable association between abnormal P-wave axis (aPWA) and increased future risk of atrial fibrillation (AF).
      • Maheshwari A.
      • Norby F.L.
      • Soliman E.Z.
      • Koene R.
      • Rooney M.
      • O'Neal W.T.
      • Alonso A.
      • Chen L.Y.
      Refining prediction of atrial fibrillation risk in the general population with analysis of P-wave axis (from the Atherosclerosis Risk in Communities Study).
      The incorporation of aPWA as a variable to the Cohorts for Heart and Aging Research in Genomic Epidemiology-AF risk score augmented the AF risk prediction.
      • Maheshwari A.
      • Norby F.L.
      • Soliman E.Z.
      • Koene R.
      • Rooney M.
      • O'Neal W.T.
      • Alonso A.
      • Chen L.Y.
      Refining prediction of atrial fibrillation risk in the general population with analysis of P-wave axis (from the Atherosclerosis Risk in Communities Study).
      • Alonso A.
      • Krijthe B.P.
      • Aspelund T.
      • Stepas K.A.
      • Pencina M.J.
      • Moser C.B.
      • Sinner M.F.
      • Sotoodehnia N.
      • Fontes J.D.
      • Janssens A.C.
      • Kronmal R.A.
      • Magnani J.W.
      • Witteman J.C.
      • Chamberlain A.M.
      • Lubitz S.A.
      • Schnabel R.B.
      • Agarwal S.K.
      • McManus D.D.
      • Ellinor P.T.
      • Larson M.G.
      • Burke G.L.
      • Launer L.J.
      • Hofman A.
      • Levy D.
      • Gottdiener J.S.
      • Kääb S.
      • Couper D.
      • Harris T.B.
      • Soliman E.Z.
      • Stricker B.H.
      • Gudnason V.
      • Heckbert S.R.
      • Benjamin E.J.
      Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to American Journal of Cardiology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Maheshwari A.
        • Norby F.L.
        • Soliman E.Z.
        • Koene R.
        • Rooney M.
        • O'Neal W.T.
        • Alonso A.
        • Chen L.Y.
        Refining prediction of atrial fibrillation risk in the general population with analysis of P-wave axis (from the Atherosclerosis Risk in Communities Study).
        Am J Cardiol. 2017; 120: 1980-1984
        • Alonso A.
        • Krijthe B.P.
        • Aspelund T.
        • Stepas K.A.
        • Pencina M.J.
        • Moser C.B.
        • Sinner M.F.
        • Sotoodehnia N.
        • Fontes J.D.
        • Janssens A.C.
        • Kronmal R.A.
        • Magnani J.W.
        • Witteman J.C.
        • Chamberlain A.M.
        • Lubitz S.A.
        • Schnabel R.B.
        • Agarwal S.K.
        • McManus D.D.
        • Ellinor P.T.
        • Larson M.G.
        • Burke G.L.
        • Launer L.J.
        • Hofman A.
        • Levy D.
        • Gottdiener J.S.
        • Kääb S.
        • Couper D.
        • Harris T.B.
        • Soliman E.Z.
        • Stricker B.H.
        • Gudnason V.
        • Heckbert S.R.
        • Benjamin E.J.
        Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium.
        J Am Heart Assoc. 2013; 2: e000102
        • Chhabra L.
        • Sareen P.
        • Perli D.
        • Srinivasan I.
        • Spodick D.H.
        Vertical P-wave axis: the electrocardiographic synonym for pulmonary emphysema and its severity.
        Indian Heart J. 2012; 64: 40-42
        • Chhabra L.
        • Sareen P.
        • Gandagule A.
        • Spodick D.
        Computerized tomographic quantification of chronic obstructive pulmonary disease as the principal determinant of frontal P vector.
        Am J Cardiol. 2012; 109: 1046-1049
        • Chhabra L.
        • Chaubey V.K.
        • Kothagundla C.
        • Bajaj R.
        • Kaul S.
        • Spodick D.H.
        P-wave indices in patients with pulmonary emphysema: do P-terminal force and interatrial block have confounding effects?.
        Int J Chron Obstruct Pulmon Dis. 2013; 8: 245-250
        • Goudis C.A.
        Chronic obstructive pulmonary disease and atrial fibrillation: An unknown relationship.
        J Cardiol. 2017; 69: 699-705
        • Shah V.
        • Desai T.
        • Agrawal A.
        The Association between Chronic Obstructive Pulmonary Disease (COPD) and Atrial Fibrillation: a review.
        Chron Obstruct Pulmon Dis. 2016; 1: 2
        • Bajaj R.
        • Chhabra L.
        • Basheer Z.
        • Spodick D.H.
        Optimal electrocardiographic limb lead set for rapid emphysema screening.
        Int J Chron Obstruct Pulmon Dis. 2013; 8: 41-44