Given the proven effectiveness of several cardiac medications for patients with coronary
artery disease (CAD), we examined the national use of 4 classes of effective medications,
overall and by age, sex, and race/ethnicity in 2005 to 2014. We used data from the
National Health and Nutrition Examination Survey, including a self-reported diagnosis
of CAD and independently verified medication use. Weighting procedures extrapolated
our data to the adult US population with CAD. Analyses included 1,789 US adults aged
≥45 years with a history of CAD. The average age of this population was 68 years;
40% were women and 79% were non-Hispanic whites. In 2005 to 2014, 53.2% (standard
error [SE] = 1.5) reported use of angiotensin-converting enzyme inhibitor/angiotensin
receptor blockers, 58.5% (SE = 1.5) β blockers, and 67.2% (SE = 1.4) statins. Two
of these medications were used by 64.1% (SE = 1.5) of the study population and all
3 by 29.1% (SE = 1.3). In 2011 to 2014, 68.5% (SE = 2.4) of American adults with a
history of CAD reported use of aspirin. The use of statins increased from 63.1% in
2005/2006 to 76.8% in 2013/2014. Adults aged 45 to 64 years old, women, and racial/ethnic
minorities had lower use of effective cardiac medications compared with older adults,
men, and non-Hispanic whites. In conclusion, the use of statins, but not other medications,
has increased over the past 10 years among American adults with previously diagnosed
CAD. Continued targeted efforts are needed to increase the receipt of effective cardiac
medications among all US adults with CAD, especially those aged 45 to 64 years, women,
and racial/ethnic minorities.
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Article Info
Publication History
Published online: July 24, 2017
Accepted:
July 7,
2017
Received:
March 20,
2017
Footnotes
Partial support for Dr. Waring was provided by NIH (Bethesda, MD) grant KL2TR000160 . Partial support for Dr. McManus was provided by NIH (Bethesda, MD) grants 1R01HL126911-01A1 and KL2RR031981 . Partial support for Dr. Kiefe was provided by Patient-Centered Outcomes Research Institute (Washington, DC) ME-1310-07682 , NIH/NCRR (Bethesda, MD) U54 RR 026088 , and National Heart, Lung, and Blood Institute (Bethesda, MD) R01 HL126911 . Partial support for Dr. Goldberg was provided by NIH/NHLBI (Bethesda, MD) grants 1R01HL126911-01A1 , 5R01HL125089-02 , and 5R01HL115295-05 . Partial support for Nathaniel Erskine was provided by the National Heart, Lung, and Blood Institute (Bethesda, MD) ( 1T32HL120823-01 ).
See page 1228 for disclosure information.
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