Until the past century, mortality trends from coronary heart disease (CHD) and cerebrovascular
disease (CVD) were less favorable in Latin than in North America. We calculated age-standardized
mortality rates using data from the World Health Organization database over the period
1980 to 2013. To identify significant changes in trends, we performed joinpoint analysis.
Since the early 2000's, CHD mortality rates decreased by about 35% in the USA and
Canada in both genders; similar decreases were observed in some Latin American countries
(i.e., Ecuador, Puerto Rico, and Chile), whereas the decreases were smaller in the
other countries. In 2011 to 2013, the highest rates were in Venezuela (114.4/100,000
men) and Colombia (86.1/100,000 men) and the lowest ones (apart from Ecuador) in Panama,
Chile, and Argentina (from 41 to 46/100,000 men and 18 to 19/100,000 women). For CVD
mortality, a decrease by about 30% was observed in Argentina, Panama, and Uruguay
plus Colombia for women, in addition to the USA and Canada. Smaller declines were
observed in the other Latin American countries (from 23% in Colombian men to 5% in
Venezuelan men). Throughout the period, rates in Latin America remained appreciably
higher than those in North America. The highest CVD rates were observed in Brazil
(51.6/100,000 men) and the lowest ones in Canada (12.9/100,000 women). In conclusion,
trends in CHD and CVD mortality continue to be less favorable in Latin America than
in Canada and the USA. The marked excess of CVD mortality is partly or largely attributable
to inadequate control of dyslipidemia and hypertension.
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Article info
Publication history
Published online: December 17, 2016
Accepted:
November 22,
2016
Received in revised form:
November 22,
2016
Received:
October 3,
2016
Footnotes
This work was supported by the Italian Association for Cancer Research (AIRC grant N. 14360) to the IRCCS—Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy, and by MIUR (Ministero dell'Istruzione, dell'Università e della Ricerca), with an SIR (Scientific Independence of Young Researchers) 2014 grant (project RBSI1465UH) to the Università degli Studi di Milano.
See page 870 for disclosure information.
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