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Usefulness of the CHADS2 Score for Prognostic Stratification in Patients With Coronary Artery Disease Having Coronary Artery Bypass Grafting

  • Dai-Yin Lu
    Affiliations
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

    School of Medicine, National Yang-Ming University, Taipei, Taiwan

    Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan
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  • Chin-Chou Huang
    Affiliations
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

    School of Medicine, National Yang-Ming University, Taipei, Taiwan

    Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan
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  • Po-Hsun Huang
    Affiliations
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

    School of Medicine, National Yang-Ming University, Taipei, Taiwan

    Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan
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  • Jaw-Wen Chen
    Affiliations
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

    Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan
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  • Tzeng-Ji Chen
    Affiliations
    Department of Family Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

    Institute of Hospital and Health Care Administration, School of Medicine, National Yang-Ming University, Taipei, Taiwan
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  • Shing-Jong Lin
    Affiliations
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

    School of Medicine, National Yang-Ming University, Taipei, Taiwan

    Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan
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  • Wan-Leong Chan
    Affiliations
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

    Healthcare and Management Center, Taipei Veterans General Hospital, Taipei, Taiwan
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  • Chiu-Yang Lee
    Correspondence
    Corresponding author: Tel: (+886)-2-28712121x8901; fax: (+886)-2-28757656.
    Affiliations
    Division of Cardiovascular Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan
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  • Hsin-Bang Leu
    Correspondence
    Corresponding author: Tel: (+886)-2-28712121x3470; fax: (+886)-2-28757858.
    Affiliations
    Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

    School of Medicine, National Yang-Ming University, Taipei, Taiwan

    Institute of Clinical Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan
    Search for articles by this author
Published:December 17, 2016DOI:https://doi.org/10.1016/j.amjcard.2016.11.035
      Current risk model for long-term survival prediction in isolated coronary artery bypass graft surgery is complicated, whereas a simple useful model is still lacking. We aim to investigate if CHADS2 score could predict long-term outcome for patients after coronary artery bypass graft surgery. From 2000 to 2007, we identified a study cohort consisting of patients who underwent coronary bypass surgery in the Taiwan National Health Insurance Research Database. After operation, all cases were followed to track the incidence of major adverse cardiovascular events and overall mortality. During a mean 5.1-year follow-up, 638 patients experienced major cardiovascular events. Six hundred twenty-five patients passed away at the end of follow-up, whereas 204 died of cardiovascular cause. Subjects with higher CHADS2 scores had significantly higher 10-year overall mortality and cardiovascular death, as well as the incidence of major adverse cardiovascular events. After adjustment with co-morbid condition and prescribed medications, CHADS2 was independently associated with increased risks of all-cause mortality (hazard ratio 1.36, 95% CI 1.29 to 1.44) and cardiovascular mortality (hazard ratio 1.37, 95% CI 1.24 to 1.52). In conclusion, CHADS2 score provides a quick and useful tool in predicting long-term outcome for patients after coronary artery bypass surgery.
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