We read with interest the report by Cangemi et al
1
“Relation of cardiac complications in the early phase of community-acquired pneumonia
(CAP) to long-term mortality and cardiovascular events” published in the August 5th
issue of the American Journal of Cardiology. The investigators show that 18% of patients with CAP study develop intrahospital
cardiac complications, defined as myocardial infarction (MI) and atrial fibrillation.
Furthermore, the investigators prospectively show that these cardiac complications
in the early phase of CAP are associated with adverse long-term cardiovascular prognosis
(with the end point being cardiovascular death, nonfatal MI, and stroke). We commend
the investigators on their work. We would also like to ask for some clarifications
because we think that the subject of cardiac complications during CAP hospitalization
merits more clinical and scientific attention.To read this article in full you will need to make a payment
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References
- Relation of cardiac complications in the early phase of community-acquired pneumonia to long-term mortality and cardiovascular events.Am J Cardiol. 2015; 116: 647-651
- Platelet activation is associated with myocardial infarction in patients with pneumonia.J Am Coll Cardiol. 2014; 64: 1917-1925
- Cardiac complications in patients with community-acquired pneumonia: a systematic review and meta-analysis of observational studies.PLoS Med. 2011; 8: e1001048
- Cardiac complications in patients with community-acquired pneumonia: incidence, timing, risk factors, and association with short-term mortality.Circulation. 2012; 125: 773-781
- The sum of two evils: pneumonia and myocardial infarction: is platelet activation the missing link?.J Am Coll Cardiol. 2014; 64: 1926-1928
- Pathophysiology of acute coronary syndrome.Curr Atheroscler Rep. 2014; 16: 401
Article Info
Publication History
Published online: October 15, 2015
Received:
October 6,
2015
Identification
Copyright
© 2016 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Relation of Cardiac Complications in the Early Phase of Community-Acquired Pneumonia to Long-Term Mortality and Cardiovascular EventsAmerican Journal of CardiologyVol. 116Issue 4
- PreviewCommunity-acquired pneumonia (CAP) is complicated by cardiac events in the early phase of the disease. Aim of this study was to assess if these intrahospital cardiac complications may account for overall mortality and cardiovascular events occurring during a long-term follow-up. Three hundred one consecutive patients admitted to the University-Hospital, Policlinico Umberto I, with community-acquired pneumonia were prospectively recruited and followed up for a median of 17.4 months. Primary end point was the occurrence of death for any cause, and secondary end point was the occurrence of cardiovascular events (cardiovascular death, nonfatal myocardial infarction [MI], and stroke).
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