Living alone was reported to be associated with increased risk of cardiovascular disease.
There are, however, limited data on the relation between living alone and all-cause
mortality in patients with acute myocardial infarction (AMI) undergoing percutaneous
coronary intervention (PCI). The Coronary REvascularization Demonstrating Outcome
Study in Kyoto (CREDO-Kyoto) AMI registry was a cohort study of patients with AMI
enrolled in 26 hospitals in Japan from 2005 through 2007. For the current analysis,
we included those patients who underwent PCI within 24 hours of symptom onset, and
we assessed their living status to determine if living alone would be an independent
prognostic risk factor. Among 4,109 patients eligible for the current analysis of
5,429 patients enrolled in the CREDO-Kyoto AMI registry, 515 patients (12.5%) were
living alone at the time of hospital admission. The cumulative 5-year incidence of
all-cause death was 18.3% in the living alone group and 20.1% in the not living alone
group (log-rank p = 0.77). After adjusting for potential confounders, risk of the
living alone group relative to the not living alone group for all-cause death was
not significantly different (adjusted hazard ratio 0.82, 95% confidence interval 0.65
to 1.02, p = 0.08). In a subgroup analysis stratified by age, the adjusted risk for
all-cause death was also not different between the living alone group and the not
living alone group both in the older population (aged ≥75 years) and the younger population
(aged <75 years). In conclusion, living alone was not associated with higher long-term
mortality in patients with AMI who underwent PCI.
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Article info
Publication history
Published online: June 05, 2014
Accepted:
May 15,
2014
Received in revised form:
May 15,
2014
Received:
April 16,
2014
Footnotes
The current study was financially supported by the Ministry of Health, Labour and Welfare in Japan and the Pharmaceuticals and Medical Devices Agency (PMDA) in Japan. These organizations had no role in the study design, in the collection, analysis, or interpretation of data, in the writing of the reports, or in the decision to submit the article for publication.
See page 526 for disclosure information.
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© 2014 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
