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- Rationale and design of the NAGOYA HEART Study: comparison between valsartan and amlodipine regarding morbidity and mortality in patients with hypertension and glucose intolerance.J Cardiol. 2010; 56: 111-117
- Comparison between valsartan and amlodipine regarding cardiovascular morbidity and mortality in hypertensive patients with glucose intolerance: NAGOYA HEART Study.Hypertension. 2012; 59: 580-586
- Standards of medical care in diabetes.Diabetes Care. 2004; 27: S15-35
- Japan Diabetes Society Treatment Guide for Diabetes 2007 (English Version). Nankodo, Tokyo, Japan2007
- Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial.Lancet. 2004; 363: 2022-2031
- The Valsartan Antihypertensive Long-Term Use Evaluation (VALUE) trial: outcomes in patients receiving monotherapy.Hypertension. 2006; 48: 385-391
- Outcomes in subgroups of hypertensive patients treated with regimens based on valsartan and amlodipine: an analysis of findings from the VALUE trial.J Hypertens. 2006; 24: 2163-2168
- Effects of valsartan and amlodipine on cardiorenal protection in Japanese hypertensive patients: the Valsartan Amlodipine Randomized Trial.Hypertens Res. 2011; 34: 62-69
- Influence of coronary risk factors on coronary events in Japanese high-risk hypertensive patients.—Primary and secondary prevention of ischemic heart disease in a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial.Circ J. 2011; 75: 2411-2416
- Trends in the incidence, mortality, and survival rate of cardiovascular disease in a Japanese community: the Hisayama study.Stroke. 2003; 34: 2349-2354
- Explanation for the Japanese paradox: prevention of increase in coronary heart disease and reduction in stroke.J Atheroscler Thromb. 2007; 14: 278-286
- Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: principal results of a prospective randomized controlled study (MOSES).Stroke. 2005; 36: 1218-1226
- Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial.Lancet. 2004; 363: 2049-2051
- A calcium channel blocker amlodipine increases coronary blood flow via both adenosine- and NO-dependent mechanisms in ischemic hearts.J Mol Cell Cardiol. 2005; 39: 605-614
- Cardiovascular outcomes in the Irbesartan Diabetic Nephropathy Trial of patients with type 2 diabetes and overt nephropathy.Ann Intern Med. 2003; 138: 542-549
- Effects of different blood pressure-lowering regimens on major cardiovascular events in individuals with and without diabetes mellitus: results of prospectively designed overviews of randomized trials.Arch Intern Med. 2005; 165: 1410-1419
- Insulin sensitivity differs among ethnic groups with a compensatory response in beta-cell function.Diabetes Care. 2000; 23: 1353-1358
- Body fat distribution and insulin resistance in healthy Asian Indians and Caucasians.J Clin Endocrinol Metab. 2001; 86: 5366-5371
- Insulin secretion capacity in the development from normal glucose tolerance to type 2 diabetes.Diabetes Res Clin Pract. 2004; 66: S37-S43
- Insulin resistance in essential hypertension.N Engl J Med. 1987; 317: 350-357
- Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement.Circulation. 2005; 112: 2735-2752
The NAGOYA HEART Study is registered at http://clinicaltrials.gov/ct2/show/NCT00129233 (NCT00129233).
The NAGOYA HEART Study was funded and supported by Nagoya University Graduate School of Medicine (Nagoya, Japan). The Department of Cardiology, Nagoya University Graduate School of Medicine reported receiving research promotion grants (Shougaku Kifukin) from Actelion (Tokyo, Japan), Astellas (Tokyo, Japan), Bayer (Osaka, Japan), Boehringer Ingelheim (Tokyo, Japan), Chugai (Tokyo, Japan), Daiichi Sankyo (Tokyo, Japan), Dainippon Sumitomo (Osaka, Japan), Eisai (Tokyo, Japan), Fujifilm RI (Tokyo, Japan), Kaken (Tokyo, Japan), Kowa (Nagoya, Japan), Kureha (Tokyo, Japan), Medtronic (Tokyo, Japan), Mitsubishi Tanabe (Osaka, Japan), Mochida (Tokyo, Japan), MSD (Tokyo, Japan), Novartis (Tokyo, Japan), Pfizer (Tokyo, Japan), Sanofi-Aventis (Tokyo, Japan), Schering-Plough (Osaka, Japan), and Takeda (Osaka, Japan). However, the research topics of these donation grants are not restricted.
See page 1755 for disclosure information.