A 40-year-old woman from El Salvador presented with 3 months of abdominal pain and
diarrhea followed by 2 weeks of atypical chest pain and exertional dyspnea and was
diagnosed with eosinophilic endocarditis secondary to Strongyloides stercoralis infection. Transthoracic echocardiogram revealed apical masses in the left and right
ventricles and a thickened posterior mitral valve leaflet and cardiac magnetic resonance
imaging confirmed the presence of a left ventricular apical mass with diffuse subendocardial
delayed enhancement consistent with endocardial fibrosis. In conclusion, eosinophilic
endocarditis is a rare cause of restrictive cardiomyopathy characterized by endomyocardial
fibrosis and apical thrombosis and fibrosis with frequent involvement of the posterior
mitral valve leaflet.
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References
- Eosinophils are a major intravascular location for tissue factor storage and exposure.Blood. 2007; 109: 995-1002
- Deposits of eosinophil granule proteins in cardiac tissues of patients with eosinophilic endomyocardial disease.Lancet. 1987; 1: 643-647
- Cardiovascular manifestations of hypereosinophilic syndromes.Immunol Allergy Clin N Am. 2007; 27: 457-475
- Clinical and echocardiographic features of hypereosinophilic syndromes.Am J Cardiol. 2000; 86: 110-113
- Cardiac magnetic resonance imaging of eosinophilic endomyocardial disease.Int J Cardiol. 2008; 126: e50-e52
Article info
Publication history
Published online: May 13, 2013
Accepted:
March 24,
2013
Received in revised form:
March 24,
2013
Received:
February 23,
2013
Footnotes
See page 462 for disclosure information.
Identification
Copyright
© 2013 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
