Knowledge of the side effects of angiotensin-converting-enzyme (ACE) inhibitors is
a matter of current discussion. Further to the recent Readers' Comment by Roberts
et al,
1
some adverse drug reactions (ADRs) caused by ACE inhibitors are likely to be found
by allergists, but ADRs to angiotensin II receptors blockers (ARBs) may also be found.
The number of symptoms associated with these ADRs might allow them to be considered
a new “syndrome.”To read this article in full you will need to make a payment
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References
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Article Info
Publication History
Received:
August 21,
2012
Identification
Copyright
© 2012 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
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- Angiotensin-Converting Enzyme (ACE) Inhibitor Angioedema: The Silent EpidemicAmerican Journal of CardiologyVol. 109Issue 5
- PreviewAn idiosyncratic reaction to commonly prescribed angiotensin-converting enzyme (ACE) inhibitors may require tracheal intubation or a surgical airway for impending respiratory compromise due to massive tongue swelling (Figure 1).1 This is not an immunoglobulin E–mediated allergic reaction, and treatment with diphenhydramine, methylprednisolone, and epinephrine will not reverse the pathology. There are no effective pharmacologic interventions to reverse or slow this form of angioedema, although the use of fresh frozen plasma has been suggested.
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