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Isolated Left Ventricular Noncompaction in Identical Twins

      The investigators describe 35-year-old monozygotic twins who presented 6 months apart with heart failure. In conclusion, this is the first report of adult monozygotic twins with isolated left ventricular noncompaction who presented with similar clinical and echocardiographic features and abnormal twist mechanics.
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      References

        • Maron B.J.
        • Towbin J.A.
        • Thiene G.
        • Antzelevitch C.
        • Corrado D.
        • Arnett D.
        • Moss A.J.
        • Seidman C.E.
        • Young J.B.
        • American Heart Association; Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; Council on Epidemiology and Prevention
        Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention.
        Circulation. 2006; 113: 1807-1816
        • Engberding R.
        • Stöllberger C.
        • Ong P.
        • Yelbuz T.M.
        • Gerecke B.J.
        • Breithardt G.
        Isolated non-compaction cardiomyopathy.
        Dtsch Arztebl Int. 2010; 107: 206-213
        • Jenni R.
        • Oechslin E.N.
        • van der Loo B.
        Isolated ventricular non-compaction of the myocardium in adults.
        Heart. 2007; 93: 11-15
        • Stöllberger C.
        • Finsterer J.
        • Blazek G.
        Left ventricular hypertrabeculation/noncompaction and association with additional cardiac abnormalities and neuromuscular disorders.
        Am J Cardiol. 2002; 90: 899-902
        • van Dalen B.M.
        • Caliskan K.
        • Soliman O.I.
        • Kauer F.
        • van der Zwaan H.B.
        • Vletter W.B.
        • van Vark L.C.
        • Ten Cate F.J.
        • Geleijnse M.L.
        Diagnostic value of rigid body rotation in noncompaction cardiomyopathy.
        J Am Soc Echocardiogr. 2011; 24: 548-555
        • Chin T.K.
        • Perloff J.K.
        • Williams R.G.
        • Jue K.
        • Mohrmann R.
        Isolated noncompaction of left ventricular myocardium.
        Circulation. 1990; 82: 507-513
        • Weiford B.C.
        • Subbarao V.D.
        • Mulhern K.M.
        Noncompaction of the ventricular myocardium.
        Circulation. 2004; 109: 2965-2971
        • Oechslin E.N.
        • Attenhofer Jost C.H.
        • Rojas J.R.
        • Kaufmann P.A.
        • Jenni R.
        Long-term follow-up of 34 adults with isolated left ventricular noncompaction: a distinct cardiomyopathy with poor prognosis.
        J Am Coll Cardiol. 2000; 36: 493-500
        • Lofiego C.
        • Biagini E.
        • Ferlito M.
        • Pasquale F.
        • Rocchi G.
        • Perugini E.
        • Leone O.
        • Bracchetti G.
        • Caliskan K.
        • Branzi A.
        • ten Cate F.J.
        • Rapezzi C.
        Paradoxical contributions of non-compacted and compacted segments to global left ventricular dysfunction in isolated left ventricular noncompaction.
        Am J Cardiol. 2006; 97: 738-741
        • Probst S.
        • Oechslin E.
        • Schuler P.
        • Greutmann M.
        • Boyé P.
        • Knirsch W.
        • Berger F.
        • Thierfelder L.
        • Jenni R.
        • Klaassen S.
        Sarcomere gene mutations in isolated left ventricular noncompaction cardiomyopathy do not predict clinical phenotype.
        Circ Cardiovasc Genet. 2011; 4: 367-374
        • Hoedemaekers Y.M.
        • Caliskan K.
        • Michels M.
        • Frohn-Mulder I.
        • van der Smagt J.J.
        • Phefferkorn J.E.
        • Wessels M.W.
        • ten Cate F.J.
        • Sijbrands E.J.
        • Dooijes D.
        • Majoor-Krakauer D.F.
        The importance of genetic counseling, DNA diagnostics, and cardiologic family screening in left ventricular noncompaction cardiomyopathy.
        Circ Cardiovasc Genet. 2010; 3: 232-239
        • Ichida F.
        • Tsubata S.
        • Bowles K.R.
        • Haneda N.
        • Uese K.
        • Miyawaki T.
        • Dreyer W.J.
        • Messina J.
        • Li H.
        • Bowles N.E.
        • Towbin J.A.
        Novel gene mutations in patients with left ventricular noncompaction or Barth syndrome.
        Circulation. 2001; 103: 1256-1263
        • Luckie M.
        • Irwin B.
        • Nair S.
        • Greenwood J.
        • Khattar R.
        Left ventricular non-compaction in identical twins with thalassaemia and cardiac iron overload.
        Eur J Echocardiogr. 2009; 10: 509-512
        • Sallin E.A.
        Fiber orientation and ejection fraction in the human left ventricle.
        Biophys J. 1969; 9: 954-964