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Noncompaction in Neuromuscular Disorders Is Not at Variance From Noncompaction in Chromosomal Disorders, Congenital, or Non-Hereditary Disease

      We read with interest the report by Greutmann et al
      • Greutmann M.
      • Mah M.L.
      • Silversides C.K.
      • Klaassen S.
      • Attenhofer Jost C.H.
      • Jenni R.
      • Oechslin E.N.
      Predictors of adverse outcome in adolescents and adults with isolated left ventricular noncompaction.
      on the predictors of adverse outcomes in adult patients with noncompaction, also known as left ventricular hypertrabeculation (LVHT). We have the following concerns.
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      References

        • Greutmann M.
        • Mah M.L.
        • Silversides C.K.
        • Klaassen S.
        • Attenhofer Jost C.H.
        • Jenni R.
        • Oechslin E.N.
        Predictors of adverse outcome in adolescents and adults with isolated left ventricular noncompaction.
        Am J Cardiol. 2012; 109: 276-281
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        • Blazek G.
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        Frequency of stroke and embolism in left ventricular hypertrabeculation/noncompaction.
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        Heart failure, atrial fibrillation and neuromuscular disorders influence mortality in left ventricular hypertrabeculation/noncompaction.
        Cardiology. 2011; 119: 176-182
        • Finsterer J.
        • Stöllberger C.
        No rationale for a diagnostic ratio in left ventricular hypertrabeculation/noncompaction.
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      Linked Article

      • Predictors of Adverse Outcome in Adolescents and Adults With Isolated Left Ventricular Noncompaction
        American Journal of CardiologyVol. 109Issue 2
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          Isolated left ventricular noncompaction is a rare form of primary cardiomyopathy. Although increasingly diagnosed, data on the outcomes are limited. To define the predictors of adverse outcomes, we performed a retrospective analysis of a prospectively defined cohort of consecutive patients (age >14 years) diagnosed with left ventricular noncompaction at a single center. The baseline characteristics included presentation with a cardiovascular complication (i.e., decompensated heart failure, systemic embolic event, or sustained ventricular arrhythmia).
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      • Authors' Reply
        American Journal of CardiologyVol. 109Issue 7
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          We welcome the opportunity to respond to Finsterer and Stöllberger's comment and thank these investigators for their interest in our report.
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