The investigators report similar phenotypes of hypertrophic cardiomyopathy with left
ventricular apical aneurysm and thrombus in 2 brothers aged 8 years apart. This report
highlights the genetic predisposition for this unique, high-risk phenotype, the issue
of prophylactic anticoagulation, and the importance of nonstandard echocardiographic
imaging views in the assessment of these patients.
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References
- Prevalence, clinical significance, and natural history of left ventricular apical aneurysms in hypertrophic cardiomyopathy.Circulation. 2008; 118: 1541-1549
- Sustained cavity obliteration and apical aneurysm formation in apical hypertrophic cardiomyopathy.J Am Coll Cardiol. 2003; 42: 288-295
- Hypertrophic cardiomyopathy complicated by large apical aneurysm and thrombus, presenting as ventricular tachycardia.J Am Coll Cardiol. 2010; 56: 1961
Article info
Publication history
Published online: June 20, 2011
Accepted:
March 25,
2011
Received in revised form:
March 25,
2011
Received:
March 15,
2011
Identification
Copyright
© 2011 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
