Transcatheter closure of ventricular septal defects (VSDs) is now offered as primary
therapy at many institutions. We sought to evaluate the clinical feasibility and safety
of device closure of intracristal VSDs using perimembranous occluders. A total of
49 patients were diagnosed with intracristal VSDs and assigned to the intracristal
VSD group, and another 49 patients with the same size perimembranous VSDs were selected
and assigned to the perimembranous VSD group. Two types of perimembranous occluders,
symmetric and asymmetric, were used, and no difference was found between the groups
with respect to successful closure. The diameter of the intracristal VSD was 3 to
10 mm (mean 5.8 ± 1.4) on the transthoracic echocardiogram. The procedure time and
fluoroscope time in the intracristal VSD group were significantly greater than those
in the perimembranous VSD group. More defects with a subaortic rim ≤2 mm on the transthoracic
echocardiogram were present in the intracristal VSD group than in the perimembranous
VSD group; thus, more asymmetric occluders were used in the intracristal VSD group.
All devices remained in a stable position and in an optimal shape during follow-up.
In conclusion, transcatheter closure of intracristal VSDs with the perimembranous
occluder is feasible, safe, and effective.
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Article Info
Publication History
Accepted:
August 24,
2010
Received in revised form:
August 24,
2010
Received:
June 8,
2010
Identification
Copyright
© 2011 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
