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Transcatheter Device Closure of Intracristal Ventricular Septal Defects

  • Author Footnotes
    † Drs. Gu and You contributed equally to this study.
    Mingbiao Gu
    Footnotes
    † Drs. Gu and You contributed equally to this study.
    Affiliations
    Department of Cardiology, YanCheng First People's Hospital, Jiangsu Province, People's Republic of China

    Department of Cardiology, ChangHai Hospital, Second Military Medical University, Shanghai, People's Republic of China
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  • Author Footnotes
    † Drs. Gu and You contributed equally to this study.
    Xiaohua You
    Footnotes
    † Drs. Gu and You contributed equally to this study.
    Affiliations
    Department of Cardiology, ChangHai Hospital, Second Military Medical University, Shanghai, People's Republic of China
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  • Xianxian Zhao
    Affiliations
    Department of Cardiology, ChangHai Hospital, Second Military Medical University, Shanghai, People's Republic of China
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  • Xing Zheng
    Affiliations
    Department of Cardiology, ChangHai Hospital, Second Military Medical University, Shanghai, People's Republic of China
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  • Yong-Wen Qin
    Correspondence
    Corresponding author: Tel: (+86) 13-8017-24861; fax: (+86) 21-5119-0921
    Affiliations
    Department of Cardiology, ChangHai Hospital, Second Military Medical University, Shanghai, People's Republic of China
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  • Author Footnotes
    † Drs. Gu and You contributed equally to this study.
      Transcatheter closure of ventricular septal defects (VSDs) is now offered as primary therapy at many institutions. We sought to evaluate the clinical feasibility and safety of device closure of intracristal VSDs using perimembranous occluders. A total of 49 patients were diagnosed with intracristal VSDs and assigned to the intracristal VSD group, and another 49 patients with the same size perimembranous VSDs were selected and assigned to the perimembranous VSD group. Two types of perimembranous occluders, symmetric and asymmetric, were used, and no difference was found between the groups with respect to successful closure. The diameter of the intracristal VSD was 3 to 10 mm (mean 5.8 ± 1.4) on the transthoracic echocardiogram. The procedure time and fluoroscope time in the intracristal VSD group were significantly greater than those in the perimembranous VSD group. More defects with a subaortic rim ≤2 mm on the transthoracic echocardiogram were present in the intracristal VSD group than in the perimembranous VSD group; thus, more asymmetric occluders were used in the intracristal VSD group. All devices remained in a stable position and in an optimal shape during follow-up. In conclusion, transcatheter closure of intracristal VSDs with the perimembranous occluder is feasible, safe, and effective.
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      References

        • Butera G.
        • Carminati M.
        • Chessa M.
        • Piazza L.
        • Micheletti A.
        • Negura D.G.
        • Abella R.
        • Giamberti A.
        • Frigiola A.
        Transcatheter closure of perimembranous ventricular septal defects: early and long-term results.
        J Am Coll Cardiol. 2007; 50: 1189-1195
        • Carminati M.
        • Butera G.
        • Chessa M.
        • De Giovanni J.
        • Fisher G.
        • Gewillig M.
        • Peuster M.
        • Piechaud J.F.
        • Santoro G.
        • Sievert H.
        • Spadoni I.
        • Walsh K.
        Transcatheter closure of congenital ventricular septal defects: results of the European Registry.
        Eur Heart J. 2007; 28: 2361-2368
        • Holzer R.
        • Balzer D.
        • Cao Q.L.
        • Lock K.
        • Hijazi Z.M.
        Device closure of muscular ventricular septal defects using the Amplatzer muscular ventricular septal defect occluder: immediate and mid-term results of septal defect occluder: immediate and mid-term results of a U.S. registry.
        J Am Coll Cardiol. 2004; 43: 1257-1263
        • Qin Y.W.
        • Chen J.M.
        • Zhao X.X.
        • Liao D.
        • Mu R.B.
        • Wang S.Q.
        • Wu H.
        • Guo H.X.
        Transcatheter closure of perimembranous ventricular septal defect using a modified double-disk occluder.
        Am J Cardiol. 2008; 101: 1781-1786
        • Gu M.B.
        • You X.H.
        • Zhao X.X.
        • Zheng X.
        • Li W.P.
        • Qin Y.W.
        Transcatheter closure of perimembranous ventricular septal defects using a novel wire-maintaining technique.
        Catheter Cardiovasc Interv. 2010; 75: 66-71
        • Hijazi Z.M.
        • Hakim F.
        • Haweleh A.A.
        • Madani A.
        • Tarawna W.
        • Hiari A.
        • Cao Q.L.
        Catheter closure of perimembranous ventricular septal defects using the new Amplatzer membranous VSD occluder: initial clinical experience.
        Catheter Cardiovasc Interv. 2002; 56: 508-515
        • Fu Y.C.
        • Bass J.
        • Amin Z.
        • Radtke W.
        • Cheatham J.P.
        • Hellenbrand W.E.
        • Balzer D.
        • Cao Q.L.
        • Hijazi Z.M.
        Transcatheter closure of perimembranous ventricular septal defects using the new Amplatzer membranous VSD occluder: results of the U.S. phase I trial.
        J Am Coll Cardiol. 2006; 47: 319-325
        • Minette M.S.
        • Sahn D.J.
        Ventricular septal defects.
        Circulation. 2006; 114: 2190-2197