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      We read with interest comments of Drs. Hof and Loh. They appropriately point out the facts that we discussed in the limitations section of our meta-analysis, which include the different methods used in these studies to determine left atrial (LA) size and function. We agree with Drs. Hof and Loh that LA volume is a better representation of true LA size,
      • Abhayaratna W.P.
      • Seward J.B.
      • Appleton C.P.
      • Douglas P.S.
      • Oh J.K.
      • Tajik A.J.
      • Tsang T.S.
      LA size: physiologic determinants and clinical applications.
      • Parikh S.S.
      • Jons C.
      • McNitt S.
      • Daubert J.P.
      • Schwarz K.Q.
      • Hall B.
      Predictive capability of left atrial size measured by CT, TEE, and TTE for recurrence of atrial fibrillation following radiofrequency catheter ablation.
      which was the basis of our study aim: to systematically review the effects of radiofrequency catheter ablation (RFCA) on LA volumes and function in addition to LA size in patients with atrial fibrillation (AF).
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      Linked Article

      • Left Atrial Size and Function After Catheter Ablation of Atrial Fibrillation: Comparing Apples and Oranges
        American Journal of CardiologyVol. 107Issue 1
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          We read with interest the meta-analysis of Jeevanantham et al1 titled “Meta-Analysis of the Effect of Radiofrequency Catheter Ablation on Left Atrial Size, Volumes and Function in Patients With Atrial Fibrillation,” published in the May 2010 issue of The American Journal of Cardiology. The relevance of the investigators' report is evident, because, as they correctly stated, the effects of catheter ablation on the left atrium are still unknown. After analyzing 17 reports concerning this subject, the investigators concluded that left atrial (LA) size decreases after ablation of atrial fibrillation (AF) and that LA function remains unaffected.
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