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United States Stock Market Performance and Acute Myocardial Infarction Rates in 2008–2009 (from the Duke Databank for Cardiovascular Disease)

Published:October 21, 2010DOI:https://doi.org/10.1016/j.amjcard.2010.07.027
      We sought to examine the relation between the United States economic decrease in 2008 and cardiovascular events as measured by local acute myocardial infarction (AMI) rates. Mental stress and traumatic events have been shown to be associated with increased risk of MI in patients with ischemic heart disease. This was an observational study of data from the Duke Databank for Cardiovascular Disease and includes patients undergoing angiography for evaluation of ischemic heart disease from January 2006 to July 2009. Patients with AMI occurring within 3 days before catheterization were used to calculate AMI rates. Stock market values were examined to determine the period of severe economic decrease, and time trends in AMI rates were examined over the same period. Time series models were used to assess the relation between United States stock market National Association of Securities Dealers Automated Quotation (NASDAQ) and rates of AMI. Of 11,590 patients included in the study cohort, 2,465 patients had an AMI during this period. Time series analysis showed a significant increase in AMI rates during a period of stock market decrease from October 2008 to April 2009 (p = 0.003), which remained statistically significant when adjusted for seasons (p = 0.02). In conclusion, unadjusted and adjusted analyses of patients in the Duke Databank for Cardiovascular Disease indicated a significant correlation between a period of stock market decrease and increased AMI rates in our local cohort.
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      Linked Article

      • Exercise Training, Cardiorespiratory Fitness, and Cardiovascular Triggers
        American Journal of CardiologyVol. 107Issue 8
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          We read with interest the report by Fiuzat et al,1 using the Duke Databank for Cardiovascular Disease, suggesting an increase in acute myocardial infarction (AMI) associated with the downturn in stock market values from October 2008 to April 2009. In their discussion, the investigators cited the New Orleans experience relative to the incidence of AMI during the Hurricane Katrina era.2,3 They referenced Gautam et al's2 report (from Tulane Medical Center), which demonstrated a dramatic, threefold increase in the number of patients who presented with AMI after February 2006 (when Tulane Medical Center reopened with complete onsite catheterization services); the increased incidence of acute cardiovascular (CV) events persisted during the entire 2-year study period.
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