The American Journal of Cardiology recently published a reported titled “Lipid-Lowering Efficacy of Red Yeast Rice in
a Population Intolerant to Statins.”
1
The investigators reported that 25 patients with known histories of intolerance to
statin drugs, when treated with red yeast rice, averaged a 21% decrease in low-density
lipoprotein cholesterol, with few side effects. In this uncontrolled study, patients
were allowed to purchase their own choices of red yeast rice products, and their selections
were not reported. The “Discussion” section ends with the recommendation “Producing
red yeast rice under controlled conditions could provide a widely available and safe
dietary supplement for lowering cholesterol.”To read this article in full you will need to make a payment
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References
- Lipid-lowering efficacy of red yeast rice in a population intolerant to statins.Am J Cardiol. 2010; 105: 664-666
- Identification and chemical profiling of monacolins in red yeast rice using high-performance liquid chromatography with photodiode array detector and mass spectrometry.J Pharm Biomed Anal. 2004; 35: 1101-1112
- An analysis of nine proprietary Chinese red yeast rice dietary supplements: implications of variability in chemical profile and contents.J Altern Complement Med. 2001; 7: 133-139
- Warning Letter: Swanson Health Products, Inc..(Accessed on April 13, 2010)
- Warning Letter: Sunburst Biorganics.(Accessed on April 13, 2010)
Article info
Publication history
Received:
April 13,
2010
Identification
Copyright
© 2010 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
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- Lipid-Lowering Efficacy of Red Yeast Rice in a Population Intolerant to StatinsAmerican Journal of CardiologyVol. 105Issue 5
- PreviewChinese red yeast rice is a dietary supplement containing monacolins, unsaturated fatty acids, and phytosterols capable of lowering low-density lipoprotein (LDL) cholesterol. Few studies have reported on its use in clinical practice or in statin-intolerant patients. We reviewed approximately 1,400 clinical charts and identified 25 patients treated with red yeast rice for ≥4 weeks. The patients were included if they had pre- and post-treatment lipid levels without simultaneous changes in other lipid-lowering medications.
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