Advertisement
Arrhythmias and conduction disturbance| Volume 102, ISSUE 12, P1674-1676, December 15, 2008

Feasibility and Safety of Remote-Controlled Magnetic Navigation for Ablation of Atrial Fibrillation

Published:November 03, 2008DOI:https://doi.org/10.1016/j.amjcard.2008.08.012
      Radiofrequency ablation for atrial fibrillation (AF) involves complex catheter manipulation resulting in prolonged procedure time and fluoroscopy exposure. Remote magnetic navigation (RMN) represents a novel approach toward improving the ability to perform complex ablation. Forty patients underwent ablation for AF, 20 using RMN (NIOBE II, Stereotaxis, Inc) with a 4-mm-tip magnetic catheter (Celsius, Biosense Webster) and 20 using a conventional 8-mm-tip bidirectional ablation catheter (Blazer, Boston Scientific). All patients underwent a combined wide area circumferential ablation and segmental pulmonary vein (PV) isolation using a circular mapping catheter and cavotricuspid isthmus ablation for right atrial flutter. The procedural end point was PV entrance block. There was no difference in atrial size, left ventricular systolic function, or type of AF between groups. PV entrance block was achieved in all patients. Mean procedure time was 279 ± 60 minutes in the conventional group versus 209 ± 56 minutes in the RMN group (p <0.001). Mean fluoroscopy time in the conventional group was 58.6 ± 21 minutes versus 19.5 ± 9.8 in the RMN group (p <0.001). At 1 year there were 15 patients in the conventional group and 16 in the RMN group free from clinical AF and off antiarrhythmic drugs (p = NS). There were 2 additional ablations performed for atypical atrial flutter in the conventional group and 3 in the RMN group (p = ns). Ablation catheter char formation was not observed. There were no procedural complications. In conclusion, radiofrequency ablation of AF performed with RMN is safe and feasible. Compared with conventional hand-navigated ablation, RMN ablation results in similar clinical outcomes with decreased fluoroscopy and procedure times.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to American Journal of Cardiology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Faddis M.
        • Blume W.
        • Dehne J.
        • Lindsay B.
        A novel, magnetically guided catheter for endocardial mapping and radiofrequency ablation.
        Circulation. 2002; 106: 2980-2985
        • Faddis M.
        • Chen J.
        • Osborne J.
        • Talcott M.
        • Lindsay B.
        Magnetic guidance system for cardiac electrophysiology: a prospective trial of safety and efficacy in humans.
        J Am Coll Cardiol. 2003; 42: 1952-1959
        • Ernst S.
        • Ouyang F.
        • Linder C.
        • Hertting K.
        • Stahl F.
        • Chun J.
        • Hachiya H.
        • Bansch D.
        • Antz M.
        • Kuck K.H.
        Initial experience with remote catheter ablation using a novel magnetic navigation system: magnetic remote catheter ablation.
        Circulation. 2004; 109: 1472-1475
        • Greenberg S.
        • Blume W.
        • Faddis M.
        • Finney J.
        • Hall A.
        • Talcott M.
        • Lindsay B.
        Remote controlled magnetically guided pulmonary vein isolation in canines.
        Heart Rhythm. 2006; 3: 71-76
        • Pappone C.
        • Vicedomini G.
        • Manguso F.
        • Gugliotta F.
        • Mazzone P.
        • Gulletta S.
        • Sora N.
        • Sala S.
        • Marzi A.
        • Augello G.
        • et al.
        Robotic magnetic navigation for atrial fibrillation ablation.
        J Am Coll Cardiol. 2006; 47: 1390-1400
        • Di Biase L.
        • Fahmy T.
        • Patel D.
        • Bai R.
        • Civello K.
        • Wanzi O.
        • Kanj M.
        • Elayi C.
        • Ching C.
        • Khan M.
        • et al.
        Remote magnetic navigation: human experience in pulmonary vein ablation.
        J Am Coll Cardiol. 2007; 50: 868-874
        • Oral H.
        • Scharf C.
        • Chugh A.
        • Hall B.
        • Cheung P.
        • Good E.
        • Veerareddy S.
        • Pelosi Jr, F.
        • Morady F.
        Catheter ablation of paroxysmal atrial fibrillation: segmental pulmonary vein ostial ablation versus left atrial ablation.
        Circulation. 2003; 108: 2355-2360
        • Marrouche N.
        • Dresing T.
        • Cole C.
        • Bash D.
        • Saad E.
        • Balaban K.
        • Pavis S.
        • Schweikert R.
        • Saliba W.
        • Abdul-Karim A.
        • et al.
        Circular mapping and ablation of the pulmonary vein for treatment of atrial fibrillation.
        J Am Coll Cardiol. 2002; 40: 464-474
        • Haïssaguerre M.
        • Jaïs P.
        • Shah D.
        • Garrigue S.
        • Takahashi A.
        • Lavergne T.
        • Hocini M.
        • Peng J.
        • Roudaut R.
        • Clémenty J.
        Electrophysiological end point for catheter ablation of atrial fibrillation initiated from multiple pulmonary venous foci.
        Circulation. 2000; 101: 1409-1417
        • Pappone C.
        • Oreto G.
        • Lamberti F.
        • Vicedomini G.
        • Loricchio M.
        • Shpun S.
        • Rillo M.
        • Calabrò M.
        • Conversano A.
        • Ben-Haim S.
        • Cappato R.
        • Chierchia S.
        Catheter ablation of paroxysmal atrial fibrillation using a 3D mapping system.
        Circulation. 1999; 100: 1203-1208
        • Oral H.
        • Knight B.
        • Ozaydin M.
        • Chugh A.
        • Lai S.
        • Scharf C.
        • Hassan S.
        • Greenstein R.
        • Han J.
        • Pelosi F.
        • Strickberger S.
        • Morady F.
        Segmental ostial ablation to isolate the pulmonary veins during atrial fibrillation: feasibility and mechanistic insights.
        Circulation. 2002; 106: 1256-1262
        • Chen X.
        • Pehrson S.
        • Svendsen J.
        Feasibility and safety of remote magnetic navigation for ablation of atrial fibrillation.
        Eur Heart J. 2007; 28S: 164