• James A. Reiffel
    Address for reprints: James A. Reiffel, MD, Columbia University College of Physicians and Surgeons, 161 Fort Washington Ave, Suite 349, New York, New York 10032
    Columbia University College of Physicians and Surgeons, New York, New York, USA
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      Some might assume that the totality of knowledge, as with energy and matter, should be finite. If so, then the more we know, the less we should still have to learn. However, as applied to atrial fibrillation (AF), clearly this hypothesis does not yet appear to hold true. AF has, no doubt, been part of the list of ailments to which we humans have been subject since the time of our evolution from other primates. However, AF was, no doubt, relatively inconsequential until our life span became such that we now survive until the ages at which AF becomes common, poorly tolerated, and clinically significant.
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