Omega-3 fatty acid ethyl esters have well-known triglyceride-lowering properties and
were shown >30 years ago to inhibit platelet function. With the recent US Food and
Drug Administration (FDA) approval of these agents for treating severe triglyceride
elevations, concerns about excess bleeding naturally arise. However, an objective
assessment of the evidence for clinically significant bleeding reveals that such concerns
are unfounded. As such, the benefits of triglyceride lowering with omega-3 fatty acids
more than outweigh any theoretical risks for increased bleeding.
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Article Info
Publication History
Published online: November 30, 2006
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© 2007 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
