Advertisement

Association of Hemoglobin A1c Level With the Severity of Coronary Artery Disease in Patients With Diabetes Mellitus

Published:February 14, 2006DOI:https://doi.org/10.1016/j.amjcard.2005.10.039
      Coronary angiography was performed in 152 men and 163 women with diabetes mellitus (mean age 55 ± 8 years) because of chest pain. The mean hemoglobin A1c level was 6.66 ± 0.58% in 132 patients with 0-vessel coronary artery disease (CAD), 8.00 ± 0.84% in 40 patients with 1-vessel CAD, 8.83 ± 1.45% in 76 patients with 2-vessel CAD, and 10.40 ± 2.28% in 67 patients with 3- or 4-vessel CAD. There was a significant increasing trend of hemoglobin A1c levels over the increasing number of vessels with CAD (p <0.0001).
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to American Journal of Cardiology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Stemmer E.A.
        Diabetes mellitus and vascular disease.
        in: Aronow W.S. Stemmer E.A. Wilson S.E. Vascular Disease in the Elderly. Futura, Armonk, NY1997: 199-220
        • Ness J.
        • Nassimiha D.
        • Feria M.I.
        • Aronow W.S.
        Diabetes mellitus in older African-Americans, Hispanics, and whites in an academic hospital-based geriatrics practice.
        Coron Artery Dis. 1999; 10: 343-346
        • DeLuca A.J.
        • Saulle L.N.
        • Aronow W.S.
        • Ravapati G.
        • Weiss M.B.
        Prevalence of silent myocardial ischemia in persons with diabetes mellitus or impaired glucose tolerance and association of hemoglobin A1c with prevalence of silent myocardial ischemia.
        Am J Cardiol. 2005; 95: 1472-1474
        • Kato T.
        • Chan M.C.Y.
        • Gao S.-Z.
        • Schroeder J.S.
        • Yokota M.
        • Murohara T.
        • Iwase M.
        • Noda A.
        • Hunt S.A.
        • Valantine H.A.
        Glucose intolerance, as reflected by hemoglobin A1c level, is associated with the incidence and severity of transplant coronary artery disease.
        J Am Coll Cardiol. 2004; 43: 1034-1041
        • King D.E.
        • Mainous III, A.G.
        • Buchanan T.A.
        • Pearson W.S.
        C-reactive protein and glycemic control in adults with diabetes.
        Diabetes Care. 2003; 26: 1535-1539
        • Schillinger M.
        • Exner M.
        • Amighi J.
        • Mlekusch W.
        • Sabeti S.
        • Rumpold H.
        • Wagner O.
        • Minar E.
        Joint effects of C-reactive protein and glycated hemoglobin in predicting future cardiovascular events of patients with advanced atherosclerosis.
        Circulation. 2003; 108: 2323-2328