Advertisement

Long-term follow-up of patients with obstructive hypertrophic cardiomyopathy treated with dual-chamber pacing

      In this study, patients with obstructive hypertrophic cardiomyopathy (HC) were treated with dual-chamber pacemaker therapy. Long-term follow-up analysis showed that dual-chamber pacemaker therapy in selected patients resulted in a significant reduction in symptoms and in the left ventricular outflow tract gradient, which was maintained up to 10 years after implantation. Dual-chamber pacing is of potential long-term benefit in selected groups of patients with obstructive HC.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to American Journal of Cardiology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Doolan A.
        • Nguyen L.
        • Semsarian C.
        Hypertrophic cardiomyopathy: from “heart tumour” to a complex molecular genetic disorder.
        Heart Lung Circ. 2004; 13: 15-25
        • Fananapazir L.
        • Epstein N.D.
        • Curiel R.V.
        • Panza J.A.
        • Tripodi D.
        • McAreavey D.
        Long-term results of dual chamber (DDD) pacing in obstructive hypertrophic cardiomyopathy.
        Circulation. 1994; 90: 2731-2742
        • McDonald K.M.
        • Maurer B.
        Permanent pacing as treatment for hypertrophic cardiomyopathy.
        Am J Cardiol. 1991; 68: 108-110
        • Slade A.K.
        • Sadoul N.
        • Shapiro L.
        • Chojnowska L.
        • Simon J.P.
        • Saumarez R.C.
        • Dodinot B.
        • Camm A.J.
        • McKenna W.J.
        • Aliot E.
        DDD pacing in hypertrophic cardiomyopathy: a multicentre clinical experience.
        Heart. 1996; 75: 44-49
        • Maron B.J.
        • Nishimura R.A.
        • McKenna W.J.
        • Rakowski H.
        • Josephson M.E.
        • Kieval R.S.
        Assessment of permanent dual-chamber pacing as a treatment for drug-refractory symptomatic patients with obstructive hypertrophic cardiomyopathy: a randomised, double-blind, crossover study (M-PATHY).
        Circulation. 1999; 99: 2927-2933
        • Gadler F.
        • Linde C.
        • Daubert C.
        • McKenna W.
        • Meisel E.
        • Aliot E.
        • Chojnowska L.
        • Guize L.
        • Gras D.
        • Jeanrenaud X.
        • et al.
        Significant improvement of quality of life following atrioventricular synchronous pacing in patients with hypertrophic obstructive cardiomyopathy.
        Eur Heart J. 1999; 20: 1044-1050