Abstract
To determine whether the inflammatory response is equally involved in the pathogenesis
of restenosis after coronary stenting and directional coronary atherectomy, we assessed
restenotic lesions with immunohistochemical methods. Levels of C-reactive protein
and macrophages were greater in patients with in-stent restenosis than in those with
restenosis after directional coronary atherectomy. This suggests that the inflammatory
response is more involved in the pathogenesis of in-stent restenosis than in restenosis
after directional coronary atherectomy.
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Article info
Publication history
Accepted:
March 15,
2004
Received in revised form:
March 15,
2004
Received:
October 30,
2003
Footnotes
☆This study was supported in part by the Grants-in-Aid for Scientific Research on Priority Areas (B-2) and the 21st Century COE Program (Life Science) of the Ministry of Education, Science, Sports, and Culture, Tokyo, Japan.
Identification
Copyright
© 2004 Excerpta Medica Inc. Published by Elsevier Inc. All rights reserved.
