Measurement of the pulmonary-to-systemic blood flow ratio (Qp/Qs) in patients with
congenital heart disease and shunting lesions may be useful for determining the need
for intervention or assessing outcome postprocedure. Frequently used methods to calculate
Qp/Qs, such as invasive oximetry, first-pass radionuclide angiography, and Doppler
echocardiography have limitations.
1
Phase-velocity cine magnetic resonance imaging (PVC MRI) is a noninvasive technique
to measure blood flow that has been demonstrated to be accurate in vitro and in vivo.
2
,
3
,
4
,
5
,
6
We have previously reported that subjects without a shunt (n = 20) had a mean Qp/Qs
of 0.99 ± 0.10 by PVC MRI.
3
The aim of this study was to prospectively evaluate the accuracy, reproducibility,
and interobserver variability of PVC MRI measurements of Qp/Qs in subjects with a
known shunt. Oximetry at catheterization was selected for comparison because this
remains the most widely accepted clinical standard.To read this article in full you will need to make a payment
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Article Info
Publication History
Accepted:
March 14,
2003
Received in revised form:
March 14,
2003
Received:
January 10,
2003
Footnotes
☆This study was supported in part by Grant M01-RR02172 NIH/NCRR/GCRC at Children’s Hospital, Boston,
Identification
Copyright
© 2003 Excerpta Medica Inc. Published by Elsevier Inc. All rights reserved.
