Previous studies using Doppler and M-mode echocardiography have demonstrated that
abnormalities of left ventricular (LV) diastolic relaxation are sensitive markers
of early myocardial dysfunction. Tissue Doppler echocardiography and color M-mode
propagation velocity (Vp) are novel noninvasive techniques that provide an estimate
of LV relaxation
1
,
2
,
3
and are less dependent on preload.
4
,
5
Furthermore, mitral inflow early filling (E) can be used in conjunction with tissue
Doppler echocardiography early diastolic velocity (EM) and Vp to estimate LV filling pressures.
3
,
4
The present study examines whether subclinical diastolic dysfunction is found in
asymptomatic type 1 diabetic patients, and evaluates the relation between diastolic
dysfunction and glycemic control using novel echocardiographic techniques.To read this article in full you will need to make a payment
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References
- An index of early left ventricular filling that combined with pulsed Doppler peak E velocity may estimate capillary wedge pressure.J Am Coll Cardiol. 1997; 29: 448-454
- Myocardial wall velocity assessment by pulsed Doppler tissue imaging.Am Heart J. 1996; 132: 648-656
- New Doppler echocardiographic applications for the study of diastolic function.J Am Coll Cardiol. 1998; 32: 865-875
- Doppler tissue imaging.J Am Coll Cardiol. 1997; 30: 1527-1533
- Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function.J Am Coll Cardiol. 1997; 30: 474-480
- Echocardiographic assessment of left ventricular hypertrophy.Am J Cardiol. 1986; 57: 450-458
- Clinical utility of Doppler echocardiography and tissue Doppler imaging in the estimation of left ventricular filling pressures.Circulation. 2000; 102: 1788-1794
- Diastolic dysfunction in normotensive men with well-controlled type 2 diabetes.Diabetes Care. 2001; 24: 5-10
- Impact of left ventricular diastolic dysfunction on maximal treadmill performance in normotensive subjects with well-controlled type 2 diabetes mellitus.Am J Cardiol. 2000; 85: 473-477
- Prevalence of diastolic dysfunction in normotensive, asymptomatic patients with well-controlled type 2 diabetes mellitus.Am J Cardiol. 2001; 87: 320-323
- Retinopathy, and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy.N Engl J Med. 2000; 342: 381-389
- Muscle capillary basement-membrane thickness and long-term glycemia in type I diabetes mellitus.N Engl J Med. 1984; 311: 694-698
- Capillary basement membranes in diabetes.Diabetes. 1983; 32: 96-100
- The impact of diabetes on left ventricular filling pattern in normotensive and hypertensive adults.J Am Coll Cardiol. 2001; 37: 1943-1949
- Relation between complications of type I diabetes mellitus and collagen-linked fluorescence.N Engl J Med. 1986; 314: 403-408
- Lipoprotein glycation and its metabolic consequences.Diabetes. 1992; 41: 67-73
- Lilly Lecture 1993. Glycation and diabetic complications.Diabetes. 1994; 43: 836-841
- Advanced glycosylation end products in tissue and the biochemical basis of diabetic complications.N Engl J Med. 1988; 318: 1315-1321
- Effects of glucose intolerance on myocardial function and collagen-linked glycation.Diabetes. 1999; 48: 1443-1447
- Glycation products and the pathogenesis of diabetic complications.Diabetes Care. 1992; 15: 1835-1843
Article info
Publication history
Accepted:
March 11,
2003
Received in revised form:
March 11,
2003
Received:
October 25,
2002
Identification
Copyright
© 2003 Excerpta Medica Inc. Published by Elsevier Inc. All rights reserved.