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Etiologies of left bundle branch block and correlations with hemodynamic and angiographic findings

  • Abnash C. Jain
    Affiliations
    Department of Medicine, Section of Cardiology, West Virginia University School of Medicine, Robert C. Byrd Health Sciences Center, Morgantown, West Virginia, USA
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  • Mahaveer C. Mehta
    Correspondence
    Dr. Mehta’s address is: Section of Cardiology, West Virginia University, 2203 Robert C. Byrd Health Sciences Center South, PO Box 9157, Morgantown, West Virginia 26506-9157, USA.
    Affiliations
    Department of Medicine, Section of Cardiology, West Virginia University School of Medicine, Robert C. Byrd Health Sciences Center, Morgantown, West Virginia, USA
    Search for articles by this author
      Eppinger and Rothberger
      • Eppinger H.
      • Rothberger C.J.
      Zur Analyse Des Elektrokardiogramms.
      introduced the concept of bundle branch block (BBB) 60 years ago in Vienna. The causes of left BBB are varied. Clinical
      • Smith S.
      • Hayes W.L.
      The prognosis of complete left bundle branch block.
      and pathologic
      • Havelda C.J.
      • Sohi G.S.
      • Flowers N.C.
      • Horan L.G.
      Pathologic correlates of the electrocardiogram complete left bundle branch block.
      studies suggest systemic hypertension and coronary artery disease (CAD) as the most common causes.
      • Smith S.
      • Hayes W.L.
      The prognosis of complete left bundle branch block.
      ,
      • Havelda C.J.
      • Sohi G.S.
      • Flowers N.C.
      • Horan L.G.
      Pathologic correlates of the electrocardiogram complete left bundle branch block.
      ,
      • Beach T.B.
      • Gracey J.G.
      • Peter R.H.
      • Grunenwald P.W.
      Benign left bundle branch block.
      ,
      • Haft J.I.
      • Herman M.V.
      • Gorlin R.
      Left bundle branch block—etiologic, hemodynamic and ventriculograpbic considerations.
      ,
      • Mehta A.
      • Jain A.C.
      • Mehta M.
      • Billie M.
      Usefulness of left atrial abnormality for predicting left ventricular hypertrophy in the presence of left bundle branch block.
      ,
      • Lewis M.
      • Dagenais G.R.
      • Friesinger G.C.
      • Ross R.S.
      Coronary angiographic appearances in patients with left bundle branch block.
      Cardiomyopathy, valvular heart disease, and several other less common causes have been described.
      • Lewis M.
      • Dagenais G.R.
      • Friesinger G.C.
      • Ross R.S.
      Coronary angiographic appearances in patients with left bundle branch block.
      It has also been known that some patients with left BBB have apparently normal hearts except for conduction system abnormalities.
      • Beach T.B.
      • Gracey J.G.
      • Peter R.H.
      • Grunenwald P.W.
      Benign left bundle branch block.
      However, the true incidence of various etiologic groups needs further corroboration by a larger study.
      • Lewis M.
      • Dagenais G.R.
      • Friesinger G.C.
      • Ross R.S.
      Coronary angiographic appearances in patients with left bundle branch block.
      Therefore, this communication provides additional data in a large number of patients regarding the various etiologies of left BBB and correlates electrocardiographic and clinical observations with left ventricular (LV) functions and coronary angiocardiographic data.
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