Several registry studies have reported clinical improvement after percutaneous myocardial
revascularization (PMR).
1
,
2
,
- Kornowski R.
- Baim D.S.
- Moses J.W.
- Hong M.K.
- Laham R.J.
- Fuchs S.
- Hendel R.C.
- Wallace D.
- Cohen D.J.
- Bonow R.O.
- Kuntz R.E.
- Leon M.B.
Short- and intermediate-term clinical outcomes from direct myocardial laser revascularization
guided by Biosense left ventricular electromechanical mapping.
Circulation. 2000; 102: 1120-1125
3
,
4
,
5
The Potential Angina Class Improvement From Intramyocardial Channels (PACIFIC) trial
reported results from the first randomized trial of PMR versus medical therapy, and
improvement in angina pectoris, treadmill time, and quality of life (QOL) 1 year after
PMR was found.
6
After encouraging results with a different holmium yttrium-aluminum-garnet (holmium-YAG)
laser and fiber optic system in a registry series,
7
a randomized trial of PMR with a 1-mm, triple pulsed optical fiber versus maximal
medical therapy was begun. This investigation reports the results of this prospective,
randomized multicenter trial using the Eclipse system (Eclipse Surgical Technologies,
Sunnyvale, California).To read this article in full you will need to make a payment
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References
- Procedural results and early clinical outcome of percutaneous transluminal myocardial revascularization.Am J Cardiol. 1999; 83: 498-501
- Short- and intermediate-term clinical outcomes from direct myocardial laser revascularization guided by Biosense left ventricular electromechanical mapping.Circulation. 2000; 102: 1120-1125
- Catheter-based percutaneous myocardial laser revascularization in patients with end-stage coronary artery disease.J Am Coll Cardiol. 1999; 34: 1663-1670
- Magnetic resonance imaging demonstrates improved regional systolic wall motion and thickening and myocardial perfusion of myocardial territories treated by laser myocardial revascularizaton.J Am Coll Cardiol. 2002; 39: 1-8
- Improvement of myocardial perfusion detected by positron emission tomography in patients with end-stage coronary artery disease treated with percutaneous myocardial laser revascularisation (abstr).Circulation. 2001; 104: 2110
- Percutaneous Transmyocardial Laser Revascularisation for Severe Angina.Lancet. 2000; 356: 1705-1710
- Percutaneous transmyocardial revascularization in patients with refractory angina (abstr).Circulation. 1998; 98: 442
- A brief self-administered questionnaire to determine functional capacity (The Duke Activity Status Index).Am J Cardiol. 1989; 64: 651-654
Pashkow FJ. Role of routine exercise electrocardiographic testing. In: Marwick TH. Cardiac Stress Testing and Imaging. 3rd ed. New York: Churchill Livingstone, 1996:10
Kornowski R, Baim DS, Moses JW, Hong MK, Laham RJ, Fuchs S, Hendel RC, Wallace D, Cohen DJ, Bonow DO, Kuntz RE, Leon MB. Short- and intermediate-term clinical outcomes from direct myocardial laser revascularization guided by Biosense left ventricular electromechanical mapping. Circulation 2000;102:1120–1125
- Blinded evaluation of laser intervention electively for angina pectoris.Circulation. 2001; 104: 2106
Article info
Publication history
Accepted:
February 24,
2003
Received in revised form:
February 24,
2003
Received:
October 17,
2002
Footnotes
This study was supported by Eclipse Surgical Technologies, Sunnyvale, California
Identification
Copyright
© 2003 Excerpta Medica Inc. Published by Elsevier Inc. All rights reserved.
