Advertisement

Determinants of angiographically silent stenoses in patients with coronary artery disease

      Approximately 20% of all patients who undergo coronary angiography for suspected coronary heart disease have normal angiograms or only mild disease (angiographic diameter stenosis [DS] <50%).
      • Kemp H.G.
      • Kronmal R.A.
      • Vlietstra R.E.
      • Frye R.L.
      Seven year survival of patients with normal or near normal coronary arteriograms a CASS registry study.
      Although the long-term prognosis is better for patients with normal angiograms or mild disease than those with critical stenoses, almost half of the patients with normal angiograms or mild disease continue to have anginal chest pain.
      • Kemp H.G.
      • Kronmal R.A.
      • Vlietstra R.E.
      • Frye R.L.
      Seven year survival of patients with normal or near normal coronary arteriograms a CASS registry study.
      ,
      • Proudfit W.L.
      • Bruschke V.G.
      • Sones Jr, F.M.
      Clinical course of patients with normal or slightly or moderately abnormal coronary arteriograms 10-year follow-up of 521 patients.
      ,
      • Foussas S.G.
      • Adamopoulou E.N.
      • Kafaltis N.A.
      • Fakiolas C.
      • Olympios C.
      • Pisimissis E.
      • Siogas K.
      • Pappas S.
      • Cokkinos D.V.
      • Sideris D.
      Clinical characteristics and follow-up of patients with chest pain and normal coronary arteries.
      Explanations for continued symptoms have included coronary artery spasm, syndrome X, noncoronary etiologies, and stenoses that are significant but angiographically unrecognized.
      • Bertrand M.E.
      • LaBlanche J.M.
      • Tilmant P.Y.
      • Thieuleux F.A.
      • Delforge M.R.
      • Carre A.G.
      • Asseman P.
      • Berzin B.
      • Libersa C.
      • Laurent J.M.
      Frequency of provoked coronary arterial spasm in 1089 consecutive patients undergoing coronary arteriography.
      ,
      • Kaski J.C.
      • Rosano G.M.
      • Collins P.
      • Nihoyannopoulos P.
      • Maseri A.
      • Poole-Wilson P.A.
      Cardiac syndrome X clinical characteristics and left ventricular function. Long-term follow-up study.
      ,
      • Thomas A.C.
      • Davies M.J.
      • Dilly S.
      • Dilly N.
      • Franc F.
      Potential errors in the estimation of coronary arterial stenosis from clinical arteriography with reference to the shape of the coronary arterial lumen.
      This report examines the frequency and predictors of angiographically occult lesions in an interventional patient population.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to American Journal of Cardiology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Kemp H.G.
        • Kronmal R.A.
        • Vlietstra R.E.
        • Frye R.L.
        Seven year survival of patients with normal or near normal coronary arteriograms.
        J Am Coll Cardiol. 1986; 7: 479-483
        • Proudfit W.L.
        • Bruschke V.G.
        • Sones Jr, F.M.
        Clinical course of patients with normal or slightly or moderately abnormal coronary arteriograms.
        Circulation. 1980; 62: 712-717
        • Foussas S.G.
        • Adamopoulou E.N.
        • Kafaltis N.A.
        • Fakiolas C.
        • Olympios C.
        • Pisimissis E.
        • Siogas K.
        • Pappas S.
        • Cokkinos D.V.
        • Sideris D.
        Clinical characteristics and follow-up of patients with chest pain and normal coronary arteries.
        Angiology. 1998; 49: 349-354
        • Bertrand M.E.
        • LaBlanche J.M.
        • Tilmant P.Y.
        • Thieuleux F.A.
        • Delforge M.R.
        • Carre A.G.
        • Asseman P.
        • Berzin B.
        • Libersa C.
        • Laurent J.M.
        Frequency of provoked coronary arterial spasm in 1089 consecutive patients undergoing coronary arteriography.
        Circulation. 1982; 65: 1299-1306
        • Kaski J.C.
        • Rosano G.M.
        • Collins P.
        • Nihoyannopoulos P.
        • Maseri A.
        • Poole-Wilson P.A.
        Cardiac syndrome X.
        J Am Coll Cardiol. 1995; 25: 807-814
        • Thomas A.C.
        • Davies M.J.
        • Dilly S.
        • Dilly N.
        • Franc F.
        Potential errors in the estimation of coronary arterial stenosis from clinical arteriography with reference to the shape of the coronary arterial lumen.
        Br Heart J. 1986; 55: 129-139