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Multiple versus single coronary plaque ruptures detected by intravascular ultrasound in stable and unstable angina pectoris and in acute myocardial infarction

      Autopsy studies have indicated that acute coronary syndromes result from spontaneous plaque rupture or erosion and subsequent thrombosis.
      • Davies M.J.
      • Thomas A.
      Thrombosis and acute coronary-artery lesions in sudden cardiac ischemic death.
      ,
      • Farb A.
      • Burke A.P.
      • Tang A.L.
      • Liang T.Y.
      • Mannan P.
      • Smialek J.
      • Virmani R.
      Coronary plaque erosion without rupture into a lipid core. A frequent cause of coronary thrombosis in sudden coronary death.
      Intravascular ultrasound (IVUS) provides detailed, high-quality tomographic images and can detect plaque rupture in vivo.

      Moriuchi M, Saito S, Takaiwa Y, Honye J, Fukui T, Horiuchi K, Takayama T, Yajima J, Shimizu T, Chiku M, Komaki K, Tanigawa N, Ozawa Y, Kanmatsuse K. Assessment of plaque rupture by intravascular ultrasound. Heart Vessels 1997; Suppl 12:178–181

      ,
      • Nagai T.
      • Luo H.
      • Atar S.
      • Lepor N.E.
      • Fishbein M.C.
      • Siegel R.J.
      Intravascular ultrasound imaging of ruptured atherosclerotic plaques in coronary arteries.
      ,
      • von Birgelen C.
      • Klinkhart W.
      • Mintz G.S.
      • Papatheodorou A.
      • Herrmann J.
      • Baumgart D.
      • Haude M.
      • Wieneke H.
      • Ge J.
      • Erbel R.
      Plaque distribution and vascular remodeling of ruptured and nonruptured coronary plaques in the same vessel an intravascular ultrasound study in vivo.
      A recent report suggested that patients with acute coronary syndromes have multiple plaque ruptures that can be detected by IVUS.
      • Rioufol G.
      • Finet G.
      • Ginon I.
      • Andre-Fouet X.
      • Rossi R.
      • Vialle E.
      • Desjoyaux E.
      • Convert G.
      • Huret J.F.
      • Tabib A.
      Multiple atherosclerotic plaque rupture in acute coronary syndrome a three-vessel intravascular ultrasound study.
      We report the clinical, angiographic, and ultrasound findings of a comparison of patients with multiple versus single plaque ruptures detected at the time of preinterventional IVUS imaging.
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