This study sought to determine the relation between fasting glucose levels, coronary
heart disease (CHD) risk factors, and the prevalence of CHD in a high-risk group of
patients attending a cardiology prevention clinic. The study was designed to address
2 questions. (1) Are increasing fasting glucose concentrations in the nondiabetic
range (≤125 mg/dl) associated with an increased burden of traditional (smoking, central
obesity, systemic hypertension, dyslipidemia) and nontraditional (e.g., fibrinogen,
homocysteine, lipoprotein(a) [Lp(a)]) CHD risk factors? (2) Are increasing blood glucose
concentrations in this range associated with a continuous and graded risk for CHD
independent of these risk factors?
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Article info
Publication history
Accepted:
November 14,
2001
Received in revised form:
November 14,
2001
Received:
August 8,
2001
Identification
Copyright
© 2002 Excerpta Medica Inc. Published by Elsevier Inc. All rights reserved.