Advertisement

Tissue Doppler-derived myocardial diastolic function distinguishes pathologic and physiologic left ventricular hypertrophy1

        The present letter rises from the article of Vinereanu et al
        • Vinereanu D.
        • Florescu N.
        • Sculthorpe N.
        • Tweddel A.C.
        • Stephens M.R.
        • Fraser A.G.
        Differentiation between pathologic and physiologic left ventricular hypertrophy by tissue Doppler assessment of long-axis function in patients with hypertrophic cardiomyopathy or systemic hypertension and in athletes.
        published in the July 1, 2001, issue of The American Journal of Cardiology, showing the ability of tissue Doppler (TD) to differentiate pathologic and physiologic left ventricular (LV) hypertrophy. By analysis of both myocardial systolic and diastolic velocities measured at multiple levels (medial, lateral, inferior, and anterior) of the mitral annulus in the apical view, the authors demonstrate that the best differentiation of pathologic LV hypertrophy (due to either hypertrophic cardiomyopathy or systemic hypertension) and athlete’s LV hypertrophy is provided by a mean systolic annular velocity <9 cm/s, with a sensitivity of 87% and a specificity of 97%. Moreover, the heterogeneity of annular velocities (“heterogeneity index”) discriminates between the 2 kinds of pathologic LV hypertrophy, it being significantly higher in hypertrophic cardiomyopathy.
        To read this article in full you will need to make a payment

        Purchase one-time access:

        Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
        One-time access price info
        • For academic or personal research use, select 'Academic and Personal'
        • For corporate R&D use, select 'Corporate R&D Professionals'

        Subscribe:

        Subscribe to American Journal of Cardiology
        Already a print subscriber? Claim online access
        Already an online subscriber? Sign in
        Institutional Access: Sign in to ScienceDirect

        References

          • Vinereanu D.
          • Florescu N.
          • Sculthorpe N.
          • Tweddel A.C.
          • Stephens M.R.
          • Fraser A.G.
          Differentiation between pathologic and physiologic left ventricular hypertrophy by tissue Doppler assessment of long-axis function in patients with hypertrophic cardiomyopathy or systemic hypertension and in athletes.
          Am J Cardiol. 2001; 8: 53-58
          • Sohn D.W.
          • Chai I.H.
          • Lee D.J.
          • Kim H.C.
          • Kim H.S.
          • Oh B.H.
          • Lee M.M.
          • Park T.B.
          • Choi Y.S.
          • Seo J.D.
          • Lee Y.W.
          Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function.
          J Am Coll Cardiol. 1997; 30: 474-480
          • Palka P.
          • Lange A.
          • Fleming A.D.
          • Donnelly J.E.
          • Dutka D.P.
          • Starkley R.I.I.
          • Dhaw T.R.
          • Sutherland G.R.
          • Fox K.A.
          Differences in myocardial velocity gradient measured throughout the cardiac cycles in patients with hypertrophic cardiomyopathy, athletes and patients with left ventricular hypertrophy due to hypertension.
          J Am Coll Cardiol. 1997; 30: 760-768
          • Severino S.
          • Caso P.
          • Galderisi M.
          • De Simone L.
          • Petrocelli A.
          • de Divitiis O.
          • Mininni N.
          Use of pulsed Doppler tissue imaging to assess regional left ventricular diastolic dysfunction in hypertrophic cardiomyopathy.
          Am J Cardiol. 1998; 82: 1394-1398
          • Galderisi M.
          • Caso P.
          • Severino S.
          • Petrocelli A.
          • De Simone L.
          • Izzo A.
          • Mininni N.
          • de Divitiis O.
          Myocardial diastolic impairment caused by left ventricular hypertrophy involves basal septum more than other walls.
          J Hypertens. 1999; 17: 685-693
          • Caso P.
          • D’Andrea A.
          • Galderisi M.
          • Liccardo B.
          • Severino S.
          • de Simone L.
          • Izzo A.
          • D’Andrea L.
          • Mininni N.
          Pulsed Doppler tissue imaging in endurance athletes.
          Am J Cardiol. 2000; 85: 1131-1136
          • D’Andrea A.
          • Caso P.
          • Galderisi M.
          • Di Maggio D.
          • Cicala S.
          • D’Andrea L.
          • Mininni N.
          • Calabrò R.
          Assessment of myocardial response to physical exercise in endurance competitive athletes by pulsed tissue Doppler.
          Am J Cardiol. 2001; 87: 1226-1230