Insulin resistance but not β-cell dysfunction is predictive of increased atherosclerosis in asymptomatic individuals without diabetes
      The insulin resistance syndrome consists of a peripheral resistance to the action of insulin combined with several metabolic abnormalities. It is associated with an increased risk of symptomatic coronary artery disease (CAD), even in the absence of clinical diabetes mellitus. Electron-beam computed tomography (EBCT) coronary artery scanning identifies asymptomatic individuals with increased coronary plaque mass, as well as increased likelihood of obstructive coronary disease and future cardiovascular events. EBCT may be used to ascertain coronary disease risk in persons with varying degrees of the insulin resistance syndrome.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to American Journal of Cardiology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect