Left ventricular function in Nigerian Africans with non–insulin-dependent diabetes mellitus

      Clinical and epidemiologic studies have suggested that patients with diabetes mellitus could develop myocardial dysfunction in the absence of epicardial coronary artery disease, systemic hypertension, or valvular heart disease.
      • Fein F.S.
      • Sonneblick E.M.
      Diabetic cardiomyopathy.
      • Regan T.J.
      Congestive heart failure in the diabetic.
      In 1972, Rubler et al
      • Rubler S.
      • Dlugash J.
      • Yueoglu Y.Z.
      • Kumral T.
      • Branwood A.W.
      • Grishmar A.
      New type of cardiomyopathy associated wityh diabetic glomerulosclerosis.
      reported 4 patients with adult-onset diabetes who had cardiomegaly and congestive heart failure in the absence of coronary artery disease or hypertension. The assessment of left ventricular (LV) function as an index of potential myocardial involvement in the diabetic patient without clinical evidence of myocardial ischemia or other cardiovascular abnormalities has become increasingly important. This is particularly true in settings like ours where diabetics with no other comorbidity factor for heart disease rarely present with heart failure. The use of echocardiography in assessing LV dimensions and function has offered a direct method for obtaining quantitative assessment of myocardial function. This study evaluates LV function in patients with non–insulin-dependent diabetes mellitus in our environment using echocardiography with a view to determining any cardiac morbidity.
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