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Lipid lowering and weight reduction by home-delivered dietary modification in coronary heart disease patients taking statins

      Whereas diet therapy remains a standard treatment for hypercholesterolemia either alone or in combination with drug treatment,
      • Yu-Poth S.
      • Zhao G.
      • Etherton T.
      • Naglak M.
      • Jonnalagadda S.
      • Kris-Etherton P.
      Effects of the National Cholesterol Education Program’s Step I and Step II dietary intervention programs on cardiovascular disease risk factors a meta-analysis.
      ,
      • Barnard R.J.
      Effects of life-style modification on serum lipids.
      ,
      • Ornish D.
      • Brown S.E.
      • Scherwitz L.W.
      • Billings J.H.
      • Armstrong W.T.
      • Ports T.A.
      • McLanahan S.M.
      • Kirkeeide R.L.
      • Brand R.J.
      • Gould K.L.
      Can lifestyle changes reverse coronary heart disease? The lifestyle heart trial.
      ,
      • Hunninghake D.B.
      • Stein E.A.
      • Dujovne C.A.
      • Harris W.S.
      • Feldman E.B.
      • Miller V.T.
      • Tobert J.A.
      • Laskarzewski P.M.
      • Quiter E.
      • Held J.
      • Taylor A.M.
      • Hopper S.
      • Leonard S.B.
      • Brewer B.K.
      The efficacy of intensive dietary therapy alone or combined with lovastatin in outpatients with hypercholesterolemia.
      ,
      • Schaefer E.J.
      • Lamon-Fava S.
      • Ausman L.
      • Ordovas J.M.
      • Clevidence B.A.
      • Judd J.T.
      • Goldin B.R.
      • Woods M.
      • Gorbach S.
      • Lichtenstein A.
      Individual variability in lipoprotein cholesterol response to National Cholesterol Education Program Step 2 diets.
      difficulties continue to exist with dietary compliance. In today’s fast food environment where fewer meals are prepared in the home, a dietary intervention program where meals and snacks are home-delivered may have beneficial effects in increasing diet adherence, while providing continuing nutrition education. This study examines if such a dietary program would result in additional serum lipid reductions beyond the reductions achieved by concurrent drug treatment for hypercholesterolemia in heart disease patients.
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      References

        • Yu-Poth S.
        • Zhao G.
        • Etherton T.
        • Naglak M.
        • Jonnalagadda S.
        • Kris-Etherton P.
        Effects of the National Cholesterol Education Program’s Step I and Step II dietary intervention programs on cardiovascular disease risk factors.
        Am J Clin Nutr. 1999; 69: 632-646
        • Barnard R.J.
        Effects of life-style modification on serum lipids.
        Arch Intern Med. 1990; 151: 1389-1394
        • Ornish D.
        • Brown S.E.
        • Scherwitz L.W.
        • Billings J.H.
        • Armstrong W.T.
        • Ports T.A.
        • McLanahan S.M.
        • Kirkeeide R.L.
        • Brand R.J.
        • Gould K.L.
        Can lifestyle changes reverse coronary heart disease? The lifestyle heart trial.
        Lancet. 1990; 336: 129-133
        • Hunninghake D.B.
        • Stein E.A.
        • Dujovne C.A.
        • Harris W.S.
        • Feldman E.B.
        • Miller V.T.
        • Tobert J.A.
        • Laskarzewski P.M.
        • Quiter E.
        • Held J.
        • Taylor A.M.
        • Hopper S.
        • Leonard S.B.
        • Brewer B.K.
        The efficacy of intensive dietary therapy alone or combined with lovastatin in outpatients with hypercholesterolemia.
        N Engl J Med. 1993; 328: 1213-1219
        • Schaefer E.J.
        • Lamon-Fava S.
        • Ausman L.
        • Ordovas J.M.
        • Clevidence B.A.
        • Judd J.T.
        • Goldin B.R.
        • Woods M.
        • Gorbach S.
        • Lichtenstein A.
        Individual variability in lipoprotein cholesterol response to National Cholesterol Education Program Step 2 diets.
        Am J Clin Nutr. 1997; 65: 823-830
        • McNamara J.R.
        • Cole T.G.
        • Contois J.H.
        • Ferguson C.A.
        • Ordovas J.M.
        • Schaefer E.J.
        Immunoseparation method for measuring low-density lipoprotein cholesterol directly from serum evaluated.
        Clin Chem. 1995; 41: 232-240
        • Selhub J.
        • Jacques P.F.
        • Bostom A.G.
        • D’Agostino R.B.
        • Wilson P.W.F.
        • Belanger A.J.
        • O’Leary D.H.
        • Wolf P.A.
        • Schaefer E.J.
        • Rosenberg I.H.
        Association between plasma homocysteine concentrations and extracranial carotid artery stenosis.
        N Engl J Med. 1995; 332: 286-291
        • Selhub J.
        • Jacques P.F.
        • Bostom A.G.
        • D’Agostino R.B.
        • Wilson P.W.F.
        • Belanger A.J.
        • O’Leary D.H.
        • Wolf P.A.
        • Rush D.
        • Schaefer E.J.
        • Rosenberg I.H.
        Relationship between plasma homocysteine, vitamin status and extracranial carotid-artery stenosis in the Framingham Study Population.
        J Nutr. 1996; 126: 1258S-1265S
        • Barnard R.J.
        • Di Lauro S.C.
        • Inkeles S.B.
        Effects of intensive diet and exercise intervention in patients taking cholesterol-lowering drugs.
        Am J Cardiol. 1997; 79: 1112-1114
        • McCarron D.A.
        • Oparil S.
        • Chait A.
        • Haynes R.B.
        • Kris-Etherton P.
        • Stern J.
        • Resnick L.M.
        • Clark S.
        • Morris C.D.
        • Hatton D.C.
        • Metz J.
        • McMahon M.
        • Holcomb S.
        • Snyder G.W.
        • Pi-Sunyer F.X.
        Nutritional management of cardiovascular risk factors.
        Arch Intern Med. 1997; 157: 169-177
        • Metz J.A.
        • Kris-Etherton P.M.
        • Morris C.D.
        • Mustad V.A.
        • Stern J.S.
        • Oparil S.
        • Chait A.
        • Haynes R.B.
        • Resnick L.M.
        • Clark S.
        • Hatton D.C.
        • McMahon M.
        • Holcomb S.
        • Snyder G.W.
        • Pi-Sunyer F.X.
        • McCarron D.A.
        Dietary compliance and cardiovascular risk reduction with a prepared meal plan compared with a self-selected diet.
        Am J Clin Nutr. 1997; 66: 373-385
        • Genest J.J.
        • McNamara J.R.
        • Salem D.N.
        • Wilson P.W.F.
        • Schaefer E.J.
        • Malinow M.R.
        Plasma homocysteine levels in men with premature coronary artery disease.
        J Am Col Cardiol. 1990; 16: 1114-1119
        • Genest J.J.
        • McNamara J.R.
        • Upson B.
        • Salem D.N.
        • Ordovas J.M.
        • Schaefer E.J.
        • Malinow M.R.
        Prevalence of familial hyperhomocysteinemia in men with premature coronary heart disease.
        Arterioscler Thromb. 1991; 11: 1129-1136