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Low-dose dobutamine imagings predicting regional improvement in left ventricular function after revascularization

      Vecchia et al
      • Vecchia L.D.
      • Storti T.
      • Cogliati C.
      • Guzzetti S.
      • Danna P.
      • Scrofani R.
      • Di Biasi P.
      • Malliani A.
      Comparison of low-dose dobutamine ventriculography with low-dose dobutamine echocardiography for predicting regional improvement in left ventricular function after coronary artery bypass grafting.
      described using low-dose dobutamine ventriculography to predict regional improvement in left ventricular function after surgical revascularization. The sensitivity and specificity for the identification of dysfunctional segments capable of recovering function was comparable between low-dose dobutamine echocardiography and ventriculography. Left ventriculography was performed only in the 30° right anterior oblique projection, which may not cover all the segments of the left ventricle. Left ventriculography was performed only after a 10-μg/kg/min dobutamine infusion, which may be responsible for a false-negative result (17%). This is due to the fact that some segments of the left ventricle may improve at the end of a 5-μg/kg/min dobutamine infusion, but deteriorate at the end of a 10-μg/kg/min dobutamine infusion. The authors concluded that this imaging technique may provide an advantage over low-dose dobutamine echocardiography in patients with suboptimal echocardiographic visualization.
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