Intravenous magnesium (Mg) is often recommended for the emergency management of selected
arrhythmias.
1
It has an established place in the treatment of drug-induced torsades de pointes
ventricular tachycardia (VT) and digoxin-induced tachyarrhythmias.
2
In contrast, there are limited data regarding the efficacy of intravenous Mg in terminating
the more common sustained monomorphic VT. Previous small series have indicated that
intravenous Mg can abort sustained monomorphic VT in experimental animals
3
and humans.
4
,
5
The primary aim of this study was to determine the efficacy of intravenous Mg in
terminating sustained monomorphic VT induced by programmed electrical stimulation
in the electrophysiology laboratory. Furthermore, the effect of Mg on VT characteristics,
cardiac electrophysiologic parameters, and its ability to prevent reinduction of VT
was assessed.To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to American Journal of CardiologyAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Magnesium sulfate therapy in certain emergency conditions.Am J Emerg Med. 1997; 15: 182-187
- Magnesium and the heart.Clin Cardiol. 1993; 16: 768-774
- Magnesium sulfate and chloride in suppression of ectopic ventricular tachycardia accompanying acute myocardial infarction.Am J Physiol. 1953; 172: 251-258
- Magnesium sulfate therapy for sustained monomorphic ventricular tachycardia.Am J Cardiol. 1989; 64: 1202-1204
Brooks R, McGovern BA, Chernow B, Garan H, Ruskin JN. Suppression of monomorphic ventricular tachycardia by intravenous magnesium chloride predicts the effectiveness of oral calcium channel blocker therapy. Circulation 1990;82(suppl III):III–82A.
- Treatment of torsade de pointes with magnesium sulfate.Circulation. 1988; 77: 392-397
Article info
Publication history
Published online: August 16, 2004
Accepted:
June 5,
2000
Received in revised form:
June 5,
2000
Received:
February 15,
2000
Identification
Copyright
© 2000 Excerpta Medica Inc. Published by Elsevier Inc. All rights reserved.
